Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person UniProt:P15372 Arr1

Class:Id	ReferenceGeneProduct:75359
_chainChangeLog	chain:1-364 added on Fri February 6 2015
_displayName	UniProt:P15372 Arr1
_timestamp	2024-02-26 04:07:27
chain	chain:1-364
checksum	0DCC764C4F890FC2
comment	FUNCTION Regulates photoreceptor cell deactivation (PubMed:8316831). Arr1 and Arr2 proteins are mediators of rhodopsin inactivation and are essential for the termination of the phototransduction cascade (PubMed:8316831). Involved in regulating normal cycles of per nuclear accumulation in brain circadian neurons and thus is important for normal circadian behavior (PubMed:36994075). In the dark, functions with Arr2 to promote the formation of cytosolic Bdbt foci, which are required for dco localization to photoreceptor nuclei where it phosphorylates and activates degradation of per (PubMed:36994075).SUBCELLULAR LOCATION Expressed specifically and abundantly in photoreceptor cells in retina and ocelli.DEVELOPMENTAL STAGE Accumulates to detectable levels by late pupation at 8 days reaching maximum levels after eclosion at 10 days.PTM Phosphorylated, but does not undergo light-induced phosphorylation.SIMILARITY Belongs to the arrestin family.
description	recommendedName: Phosrestin-2 alternativeName: Arrestin-1 alternativeName: Arrestin-A alternativeName: Phosrestin II
geneName	Arr1 ArrA CG5711
identifier	P15372
isSequenceChanged	FALSE
keyword	Cell projection Phosphoprotein Reference proteome Sensory transduction Vision
modified	[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09 [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26
name	Arr1
referenceDatabase	[ReferenceDatabase:2] UniProt
secondaryIdentifier	ARRA_DROME Q9VJA8
sequenceLength	364
species	[Species:56210] Drosophila melanogaster
(referenceEntity)	[EntityWithAccessionedSequence:75360] ARR1 [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:75363] Phospho ARR1 [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:426778] ARR1 [clathrin-coated endocytic vesicle] [Drosophila melanogaster]
(referenceSequence)	[ModifiedResidue:75362] phosphorylated residue at unknown position [ModifiedResidue:427055] O-phospho-L-serine at 361
[Change default viewing format]

No pathways have been reviewed or authored by UniProt:P15372 Arr1 (75359)