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Details on Person TRAIL binds TRAIL receptors

Class:IdReaction:75238
_displayNameTRAIL binds TRAIL receptors
_doReleaseTRUE
_timestamp2016-11-10 00:55:02
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:110071] Tschopp, Jürg, 2004-01-28
edited[InstanceEdit:5633134] Gillespie, Marc E, 2014-10-30
input[EntityWithAccessionedSequence:66186] TNFSF10 [extracellular region] [Homo sapiens]
[DefinedSet:5634815] TNFRSF10A,TNFRSF10B [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:141147] Identification and characterization of a new member of the TNF family that induces apoptosis
[LiteratureReference:5634818] TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL
[LiteratureReference:5634822] The receptor for the cytotoxic ligand TRAIL
modified[InstanceEdit:83535] Matthews, L, 2003-11-18 00:00:00
[InstanceEdit:83604] Matthews, L, 2003-11-23 12:20:00
[InstanceEdit:83683] Matthews, L, 2003-11-27 03:00:00
[InstanceEdit:83892] Matthews, L, 2003-12-10 03:30:00
[InstanceEdit:109912] Joshi-Tope, G, 2004-01-21 22:18:55
[InstanceEdit:109917] Joshi-Tope, G, 2004-01-22 15:11:19
[InstanceEdit:110070] Joshi-Tope, G, 2004-01-28 14:40:07
[InstanceEdit:141162] Gillespie, ME, 2004-09-02 19:19:13
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2648974] D'Eustachio, P, 2012-11-21
[InstanceEdit:3597633] Shamovsky, V, 2013-05-22
[InstanceEdit:5634834] Orlic-Milacic, Marija, 2014-11-06
[InstanceEdit:5634844] Orlic-Milacic, Marija, 2014-11-06
[InstanceEdit:5637454] Orlic-Milacic, Marija, 2014-11-10
[InstanceEdit:5637470] Orlic-Milacic, Marija, 2014-11-10
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTRAIL binds TRAIL receptors
TNFSF10 binds TNFRSF10A or TNFRSF10B
TRAIL Binds TRAIL Receptor-1 or TRAIL Receptor-2
TRAIL binds DR4 or DR5
output[Complex:5637465] TNFSF10:TNFRSF10A,B [plasma membrane] [Homo sapiens]
releaseDate2004-10-27
reviewed[InstanceEdit:3597630] Pop, Cristina, Salvesen, Guy S., 2013-05-22
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5634777] Orlic-Milacic, Marija, 2014-11-06
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358527] R-HSA-75238.3
summation[Summation:179243] TRAIL (TNF-related apoptosis-inducing ligand) binds TRAIL re...
(hasEvent)[Pathway:75158] TRAIL signaling [Homo sapiens]
(precedingEvent)[Reaction:75187] TRAIL:TRAIL receptor trimers bind FADD [Homo sapiens]
[Reaction:141139] Trimerization of TRAIL:TRAIL receptor complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785927] Update Tracker - [Reaction:75238] TRAIL binds TRAIL receptors - v51:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[_UpdateTracker:9788241] Update Tracker - [Reaction:75238] TRAIL binds TRAIL receptors - v43:[modifyText]
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