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Details on Person MRN 5'-3' exonuclease activity generates a short 5' overhang at ends of DSB

Class:IdReaction:75180
_displayNameMRN 5'-3' exonuclease activity generates a short 5' overhang at ends of DSB
_doReleaseFALSE
_timestamp2016-07-15 23:49:19
catalystActivity[CatalystActivity:75179] exonuclease activity of MRN [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:73965] Thompson, L, 2003-07-14 15:03:24
input[Complex:75166] DNA double-strand break ends: MRN complex [nucleoplasm] [Homo sapiens]
modified[InstanceEdit:75992] Matthews, L, 2003-09-10 06:00:00
[InstanceEdit:83604] Matthews, L, 2003-11-23 12:20:00
[InstanceEdit:83892] Matthews, L, 2003-12-10 03:30:00
[InstanceEdit:84007] Matthews, L, 2003-12-10 07:00:00
[InstanceEdit:109574] Matthews, L, 2004-01-11 23:40:00
[InstanceEdit:109776] Matthews, L, 2004-01-21 00:25:00
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameMRN 5'-3' exonuclease activity generates a short 5' overhang at ends of DSB
output[Complex:75168] DNA DSB ends containing 5' overhang:MRN complex [nucleoplasm] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8891733] R-HSA-75180.1
(precedingEvent)[Reaction:75183] Association of an helicase with 5' overhang at DSB ends and separation of DNA strands [Homo sapiens]
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No pathways have been reviewed or authored by MRN 5'-3' exonuclease activity generates a short 5' overhang at ends of DSB (75180)