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Details on Person Formation of RAD50:MRE11 complex

Class:IdReaction:75172
_displayNameFormation of RAD50:MRE11 complex
_doReleaseTRUE
_timestamp2015-08-24 17:04:45
authored[InstanceEdit:75141] Matthews, L, 2003-08-11 05:43:00
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:73965] Thompson, L, 2003-07-14 15:03:24
edited[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
input[EntityWithAccessionedSequence:75160] RAD50 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:59544] MRE11A [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5687770] Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair
[LiteratureReference:981730] The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
modified[InstanceEdit:75992] Matthews, L, 2003-09-10 06:00:00
[InstanceEdit:83892] Matthews, L, 2003-12-10 03:30:00
[InstanceEdit:84007] Matthews, L, 2003-12-10 07:00:00
[InstanceEdit:111372] Matthews, L, 2004-02-13 08:00:00
[InstanceEdit:111433] Matthews, L, 2004-02-14 01:20:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:5687761] Orlic-Milacic, Marija, 2015-04-08
[InstanceEdit:5687772] Orlic-Milacic, Marija, 2015-04-09
[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
[InstanceEdit:5693251] Orlic-Milacic, Marija, 2015-05-14
[InstanceEdit:5693618] Orlic-Milacic, Marija, 2015-05-16
[InstanceEdit:6792494] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFormation of RAD50:MRE11 complex
output[Complex:75161] RAD50:MRE11A [nucleoplasm] [Homo sapiens]
releaseDate2003-11-03
reviewed[InstanceEdit:5693179] Borowiec, James A, 2015-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359516] R-HSA-75172.3
summation[Summation:75173] MRE11 has both manganese dependent ssDNA 3'->5' exonuclease ...
(hasEvent)[Pathway:5693548] Sensing of DNA Double Strand Breaks [Homo sapiens]
(precedingEvent)[Reaction:75174] Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction [Homo sapiens]
(updatedInstance)[_UpdateTracker:9784552] Update Tracker - [Reaction:75172] Formation of RAD50:MRE11 complex - v53:[addLiteratureReference, modifyText]
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