Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person MRN [nucleoplasm]

Class:IdComplex:75164
_displayNameMRN [nucleoplasm]
_timestamp2015-03-05 05:21:28
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:75141] Matthews, L, 2003-08-11 05:43:00
hasComponent
modified[InstanceEdit:83892] Matthews, L, 2003-12-10 03:30:00
[InstanceEdit:158100] Schmidt, EE, 2005-01-19 12:00:41
[InstanceEdit:5682052] Orlic-Milacic, Marija, 2015-03-05
nameMRN
MRE11:RAD50:NBS1
MRE11:RAD50:NBN
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:371325] R-HSA-75164.1
(hasComponent)[Complex:75166] DNA double-strand break ends: MRN complex [nucleoplasm] [Homo sapiens]
[Complex:75168] DNA DSB ends containing 5' overhang:MRN complex [nucleoplasm] [Homo sapiens]
[Complex:981776] MRN:CtIP [nucleoplasm] [Homo sapiens]
[Complex:3785763] DNA DSBs:MRN [nucleoplasm] [Homo sapiens]
[Complex:5682022] Shortened telomere:MRN [nucleoplasm] [Homo sapiens]
[Complex:5687467] Microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] [Homo sapiens]
[Complex:5687502] Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] [Homo sapiens]
[Complex:5687646] Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN [nucleoplasm] [Homo sapiens]
[Complex:5687666] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] [Homo sapiens]
[Complex:9979941] HHV8 Linear DNA with extended microhomologous 3'-ssDNA overhangs:MRN [nucleoplasm] [Homo sapiens]
(input)[Reaction:3785768] MRN complex binds DNA double strand breaks [Homo sapiens]
[Reaction:5682020] MRN complex binds shortened telomeres [Homo sapiens]
(output)[Reaction:75174] Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction [Homo sapiens]
[Reaction:5687675] LIG3 ligates remaining SSBs in MMEJ [Homo sapiens]
(physicalEntity)[CatalystActivity:75179] exonuclease activity of MRN [nucleoplasm]
[CatalystActivity:75184] endonuclease activity of MRN [nucleoplasm]
(updatedInstance)[_UpdateTracker:9892579] Update Tracker - [Complex:75164] MRN [nucleoplasm] - v53:[modifyName]
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No pathways have been reviewed or authored by MRN [nucleoplasm] (75164)