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Details on Person Inactive G alpha (q) reassociates with G beta:gamma

Class:Id	Reaction:750993
_displayName	Inactive G alpha (q) reassociates with G beta:gamma
_doRelease	TRUE
_timestamp	2017-07-11 09:38:55
authored	[InstanceEdit:749459] Jupe, S, 2010-05-18
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:751025] Jupe, S, 2010-05-19
edited	[InstanceEdit:813668] Jupe, S, 2010-05-26
input	[Complex:114556] G-protein alpha (q/11):GDP [plasma membrane] [Homo sapiens] [Complex:167434] G-protein beta-gamma complex [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:751012] Structural basis of function in heterotrimeric G proteins [LiteratureReference:165196] The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
modified	[InstanceEdit:804958] Jupe, S, 2010-05-26 [InstanceEdit:813670] Jupe, S, 2010-05-26 [InstanceEdit:6814785] Orlic-Milacic, Marija, 2015-11-27 [InstanceEdit:8983501] Varusai, Thawfeek, 2017-03-24 [InstanceEdit:9012089] Varusai, Thawfeek, 2017-07-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Inactive G alpha (q) reassociates with G beta:gamma
output	[Complex:114557] Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:418582] G alpha (q) auto-inactivates by hydrolysing GTP to GDP [Homo sapiens] [Reaction:418576] Dissociation of the P2Y purinoceptor 1:Gq complex [Homo sapiens] [Reaction:397835] Thrombin-activated PARs:Gq (active) dissociate [Homo sapiens] [Reaction:428752] Dissociation of the TP:Gq complex [Homo sapiens] [Reaction:749452] The Ligand:GPCR:Gq complex dissociates [Homo sapiens] [Reaction:6814418] PDCL promotes formation of G-beta:G-gamma heterodimers [Homo sapiens] [Reaction:8850527] PDCL releases folded G-beta from TRiC/CCT [Homo sapiens]
releaseDate	2010-06-15
reviewed	[InstanceEdit:782850] D'Eustachio, P, 2010-05-21
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9012014] Varusai, Thawfeek, 2017-07-10
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105675] R-HSA-750993.4
summation	[Summation:804959] The classical model of G-protein signaling suggests that the...
(hasEvent)	[Pathway:416476] G alpha (q) signalling events [Homo sapiens]
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