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Details on Person PTRF binds the paused RNA Polymerase I complex

Class:Id	Reaction:74993
_displayName	PTRF binds the paused RNA Polymerase I complex
_doRelease	TRUE
_timestamp	2026-05-06 19:06:11
authored	[InstanceEdit:73851] Comai, L, 2003-07-03 17:13:29
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:73851] Comai, L, 2003-07-03 17:13:29
edited	[InstanceEdit:165085] Gillespie, ME, 0000-00-00 00:00:00
figure	[Figure:75837] /figures/PolI_txn_term_paused.jpg
input	[EntityWithAccessionedSequence:74981] PTRF [nucleoplasm] [Homo sapiens] [Complex:74979] paused RNA Pol I complex:45S pre-rRNA gene:pre-rRNA transcript [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:74998] Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.
modified	[InstanceEdit:75829] Gillespie, ME, 2003-09-02 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:5419295] May, Bruce, 2014-05-04 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9988367] Rothfels, Karen, 2026-05-06
name	PTRF binds the paused RNA Polymerase I complex
output	[Complex:74982] PTRF:paused RNA Pol I complex:45S pre-rRNA gene:pre-rRNA transcript [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:74994] Elongating RNA Polymerase I Transcription Complex pauses at the TTF1:Sal Box [Homo sapiens] [Reaction:74986] Elongation of pre-rRNA transcript [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360010] R-HSA-74993.3
summation	[Summation:74991] Dissociation of paused ternary complexes requires the Polyme...
(hasEvent)	[Pathway:73863] RNA Polymerase I Transcription Termination [Homo sapiens]
(precedingEvent)	[Reaction:74992] Dissociation of PTRF:RNA Polymerase I:pre-rRNA complex [Homo sapiens]
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