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Details on Person RDH10,11 oxidise 11cROL to 11cRAL

Class:Id	Reaction:74872
_displayName	RDH10,11 oxidise 11cROL to 11cRAL
_doRelease	TRUE
_timestamp	2014-04-15 10:20:20
authored	[InstanceEdit:74965] Carleton, KL, 2003-07-31 08:44:54 [InstanceEdit:2453822] Jassal, Bijay, 2012-08-17
catalystActivity	[CatalystActivity:74871] all-trans-retinol dehydrogenase (NADP+) activity of RDH10,11 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:74965] Carleton, KL, 2003-07-31 08:44:54
edited	[InstanceEdit:2453822] Jassal, Bijay, 2012-08-17
input	[SimpleEntity:29366] NADP+ [cytosol] [Complex:2454078] RLBP1:11cROL [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:2454065] Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1) [LiteratureReference:2454073] Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE
modified	[InstanceEdit:74920] Schmidt, EE, 2003-07-30 11:40:34 [InstanceEdit:74964] Schmidt, EE, 2003-07-31 08:44:50 [InstanceEdit:2453822] Jassal, Bijay, 2012-08-17 [InstanceEdit:2454089] Jassal, Bijay, 2012-08-20 [InstanceEdit:2454115] Jassal, Bijay, 2012-08-21 [InstanceEdit:2454263] Jassal, Bijay, 2012-08-22 [InstanceEdit:2470272] Jassal, Bijay, 2012-09-18 [InstanceEdit:2470325] Jassal, Bijay, 2012-09-18 [InstanceEdit:2473461] Jassal, Bijay, 2012-09-24 [InstanceEdit:2550421] Jassal, Bijay, 2012-11-02 [InstanceEdit:2586575] Jassal, Bijay, 2012-11-15 [InstanceEdit:3006583] Jassal, Bijay, 2013-01-31 [InstanceEdit:5362138] Jassal, Bijay, 2014-04-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RDH10,11 oxidise 11cROL to 11cRAL RDHs oxidise 11-cis-retinol to 11-cis-retinal
output	[SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol] [Complex:2454060] RLBP1:11cRAL [cytosol] [Homo sapiens]
precedingEvent	[Reaction:2454264] 11cROL binds to RLBP1 to form RLBP1:11cROL [Homo sapiens] [Reaction:2453833] RPE65 isomero-hydrolyses atREs to 11cROL [Homo sapiens]
releaseDate	2013-03-12
reviewed	[InstanceEdit:3006584] Blaner, William S, 2013-01-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200311] R-HSA-74872.2
summation	[Summation:2454083] Using NADP+ as cofactor, several members of the short-chain ...
(hasEvent)	[Pathway:74944] Retinal regeneration [Homo sapiens] [Pathway:2453902] The canonical retinoid cycle in rods (twilight vision) [Homo sapiens]
(precedingEvent)	[Reaction:8960973] RLBP1:11cRAL dissociates [Homo sapiens]
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No pathways have been reviewed or authored by RDH10,11 oxidise 11cROL to 11cRAL (74872)