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Details on Person The effect of the proton pump is to allow entry of [H+] ions...

Class:IdSummation:74753
_displayNameThe effect of the proton pump is to allow entry of [H+] ions...
_timestamp2004-09-20 13:52:52
created[InstanceEdit:74816] 2003-07-28 10:05:14
modified[InstanceEdit:74806] Schmidt, EE, 2003-07-28 08:28:53
[InstanceEdit:74811] Schmidt, EE, 2003-07-28 10:05:13
[InstanceEdit:141448] Matthews, L, 2004-09-20 15:43:00
textThe effect of the proton pump is to allow entry of [H+] ions into the lumen of the endosome. The net effect of this is to lower the pH of the lumen from pH 7.4 (the pH at the plasma membrane) to pH 6.0 (documented with studies using FITC-labeled insulin - a pH dependent fluorescence marker).
(summation)[Reaction:74723] Endosome acidification [Homo sapiens]
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