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Details on Person IRS1, IRS2 and IRS3 are all known to bind the regulatory sub...
| Class:Id | Summation:74739 |
| _displayName | IRS1, IRS2 and IRS3 are all known to bind the regulatory sub... |
| _timestamp | 2017-04-05 15:28:48 |
| created | [InstanceEdit:74816] 2003-07-28 10:05:14 |
| literatureReference | [LiteratureReference:8984312] Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin |
| modified | [InstanceEdit:74806] Schmidt, EE, 2003-07-28 08:28:53 [InstanceEdit:74811] Schmidt, EE, 2003-07-28 10:05:13 [InstanceEdit:77420] Schmidt, EE, 2003-10-27 06:13:17 [InstanceEdit:157832] Schmidt, EE, 2005-01-07 14:20:30 [InstanceEdit:157835] Schmidt, EE, 2005-01-07 14:38:14 [InstanceEdit:8984379] Duenas, Corina, 2017-04-05 |
| text | IRS1, IRS2 and IRS3 are all known to bind the regulatory subunit of PI3K via its SH2 domain, an interaction that itself activates the kinase activity of the PI3K catalytic subunit (Rivachandran et al. 2001). |
| (summation) | [Reaction:74737] p-Y-IRS1,p-Y-IRS2 bind PI3K [Homo sapiens] |
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No pathways have been reviewed or authored by IRS1, IRS2 and IRS3 are all known to bind the regulatory sub... (74739)