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Details on Person PI3K [cytosol]
Class:Id Complex:74693 _displayName PI3K [cytosol] _timestamp 2008-06-20 12:55:33 compartment [Compartment:70101] cytosol created [InstanceEdit:74677] Schmidt, EE, 2003-08-20 08:52:29 hasComponent
modified [InstanceEdit:75846] Schmidt, EE, 2003-09-08 11:39:12 name PI3K species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:369953] R-HSA-74693.1 (activeUnit) [PositiveGeneExpressionRegulation:9978944] Positive gene expression regulation by 'VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane]' [CatalystActivity:198361] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] [CatalystActivity:1433507] 1-phosphatidylinositol-3-kinase activity of PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] [CatalystActivity:1861701] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of PI3K:p-6Y-SYK [plasma membrane] [CatalystActivity:2029257] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of PI3K:p-6Y-SYK [plasma membrane] [CatalystActivity:2424483] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] [CatalystActivity:2730890] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] [CatalystActivity:5218825] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] [CatalystActivity:9670406] 1-phosphatidylinositol-3-kinase activity of PI3K:p-KIT mutant dimers [plasma membrane] [CatalystActivity:9672160] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of p-11Y PDGFRA extracellular domain dimers:PI3K [endoplasmic reticulum membrane] (hasComponent) [Complex:74694] p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] [Homo sapiens] [Complex:186789] PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] [Homo sapiens] [Complex:190928] Activated FGFR bound to PI3K [cytosol] [Homo sapiens] [Complex:198344] Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] [Homo sapiens] [Complex:198378] Phospho-IRS1/2:active PI3K [plasma membrane] [Homo sapiens] [Complex:201504] PTN:Phospho-ALK homodimer:PI3K [plasma membrane] [Homo sapiens] [Complex:202283] PI3K bound to TRAT [plasma membrane] [Homo sapiens] [Complex:204834] p85 bound to Tie2 [plasma membrane] [Homo sapiens] [Complex:213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] [Homo sapiens] [Complex:451720] PI3K:CD2AP:p-Nephrin:Fyn:NEPH1 [plasma membrane] [Homo sapiens] (input) [Reaction:74737] p-Y-IRS1,p-Y-IRS2 bind PI3K [Homo sapiens] [Reaction:186780] PI3-kinase binds to the active receptor [Homo sapiens] [Reaction:190929] Activated FGFR binds PI3K [Homo sapiens] [Reaction:198315] Active IRS recruits PI3K to the plasma membrane and activates it [Homo sapiens] [BlackBoxEvent:201515] Active ALK recruits PI3K [Homo sapiens] [Reaction:202203] Recruitment of PI3K to plasma membrane [Homo sapiens] [Reaction:204798] Interaction of Tie2 and p85 of PI3K [Homo sapiens] [Reaction:451758] p85 associates with both p-Nephrin and CD2AP [Homo sapiens] [Reaction:1861731] PI3K binds to p-6Y-SYK [Homo sapiens] [Reaction:2029273] PI3K binds to p-6Y-SYK [Homo sapiens]
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