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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person GRB2-1 [cytosol]

Class:IdEntityWithAccessionedSequence:74686
_displayNameGRB2-1 [cytosol]
_timestamp2016-06-10 20:11:41
compartment[Compartment:70101] cytosol
created[InstanceEdit:74677] Schmidt, EE, 2003-08-20 08:52:29
endCoordinate217
modified[InstanceEdit:77383] Schmidt, EE, 2003-10-24 07:52:24
[InstanceEdit:109781] Schmidt, EE, 2004-01-21 04:32:59
[InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08
[InstanceEdit:188944] Gopinathrao, G, 2006-10-31 10:11:13
[InstanceEdit:2006497] Orlic-Milacic, Marija, 2011-11-21
[InstanceEdit:3364050] Jupe, S, 2013-05-13
[InstanceEdit:3450990] Jupe, S, 2013-05-16
[InstanceEdit:5624357] Jupe, Steve, 2014-09-25
[InstanceEdit:8876264] Orlic-Milacic, Marija, 2016-06-10
nameGRB2-1
GRB2 isoform 1
Growth factor receptor-bound protein 2
SH2/SH3 adapter GRB2
ASH protein
Ash-L
referenceEntity[ReferenceIsoform:55928] UniProt:P62993-1 GRB2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:365976] R-HSA-74686.2
startCoordinate1
(activeUnit)[CatalystActivity:9851158] transmembrane receptor protein tyrosine kinase adaptor activity of GRB2-1:SOS1 [cytosol]
[CatalystActivity:9851162] guanyl-nucleotide exchange factor adaptor activity of GRB2-1 [cytosol]
[CatalystActivity:9851163] protein-macromolecule adaptor activity of GRB2-1:SOS1 [cytosol]
[CatalystActivity:9851193] signaling adaptor activity of GRB2-1 [cytosol]
[CatalystActivity:9851196] transmembrane receptor protein tyrosine kinase adaptor activity of GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol]
[CatalystActivity:9851546] protein-macromolecule adaptor activity of GRB2-1 [cytosol]
[CatalystActivity:9851547] enzyme-substrate adaptor activity of CBL:GRB2 [cytosol]
(hasComponent)[Complex:109797] GRB2-1:SOS1 [cytosol] [Homo sapiens]
[Complex:109799] GRB2-1:p-Y-SHC [cytosol] [Homo sapiens]
[Complex:109801] GRB2-1:p-4S-SOS1 [cytosol] [Homo sapiens]
[Complex:179849] GRB2:GAB1 [cytosol] [Homo sapiens]
[Complex:180304] GRB2:Phospho-GAB1 [cytosol] [Homo sapiens]
[Complex:180511] GRB2:Phospho-GAB1(partially dephosphorylated) [cytosol] [Homo sapiens]
[Complex:182910] CBL:GRB2 [cytosol] [Homo sapiens]
[Complex:182941] EGF:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:EPS15:Clathrin [plasma membrane] [Homo sapiens]
[Complex:182946] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] [Homo sapiens]
[Complex:182948] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] [Homo sapiens]
List all 50 refering instances
(hasMember)[DefinedSet:167211] Grb2 [cytosol] [Homo sapiens]
[DefinedSet:2197679] SH3 domain proteins [cytosol] [Homo sapiens]
[CandidateSet:9019558] RHOU effectors [cytosol] [Homo sapiens]
(input)[Reaction:109813] GRB2-1 binds SOS1 [Homo sapiens]
[Reaction:177920] Binding of GRB2 to GAB1 [Homo sapiens]
[Reaction:183052] CBL binds to GRB2 [Homo sapiens]
[Reaction:203079] Grb2 mediated activation of N-WASP [Homo sapiens]
[Reaction:204871] Interaction of Tie2 and Grb2 [Homo sapiens]
[Reaction:204925] Interaction of pAxl and Grb2 [Homo sapiens]
[Reaction:354087] Recruitment of GRB2 to p-PTK2 [Homo sapiens]
[Reaction:374687] p-Y605,Y606-KIRREL binds GRB2 [Homo sapiens]
[Reaction:388814] Grb2 binds CD28 [Homo sapiens]
[Reaction:389919] Grb2 binds pBTLA [Homo sapiens]
List all 25 refering instances
(output)[Reaction:1549564] PPTN11 dephosphorylates SPRY2 [Homo sapiens]
(physicalEntity)[CatalystActivity:9851162] guanyl-nucleotide exchange factor adaptor activity of GRB2-1 [cytosol]
[CatalystActivity:9851193] signaling adaptor activity of GRB2-1 [cytosol]
[CatalystActivity:9851546] protein-macromolecule adaptor activity of GRB2-1 [cytosol]
(requiredInputComponent)[Reaction:354165] Interaction of SOS with GRB2 bound to FADK1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9871046] Update Tracker - [EntityWithAccessionedSequence:74686] GRB2-1 [cytosol] - v39:[modifyEndCoordinate]
[_UpdateTracker:9883239] Update Tracker - [EntityWithAccessionedSequence:74686] GRB2-1 [cytosol] - v45:[modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by GRB2-1 [cytosol] (74686)
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