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Details on Person p-Y427-SHC1 [cytosol]

Class:Id	EntityWithAccessionedSequence:74684
_displayName	p-Y427-SHC1 [cytosol]
_timestamp	2015-03-27 09:24:20
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:74677] Schmidt, EE, 2003-08-20 08:52:29
endCoordinate	583
hasModifiedResidue	[ModifiedResidue:74683] O4'-phospho-L-tyrosine at 427
modified	[InstanceEdit:75845] Schmidt, EE, 2003-09-08 11:12:44 [InstanceEdit:77383] Schmidt, EE, 2003-10-24 07:52:24 [InstanceEdit:110001] Schmidt, EE, 2004-01-23 05:11:12 [InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08 [InstanceEdit:939908] Jupe, S, 2010-09-02 [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3322333] Wu, G, 2013-05-03 [InstanceEdit:3322334] Wu, G, 2013-05-03 [InstanceEdit:5685348] Jupe, Steve, 2015-03-27
name	p-Y427-SHC1 SHC transforming protein
referenceEntity	[ReferenceGeneProduct:64430] UniProt:P29353 SHC1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:370982] R-HSA-74684.1
startCoordinate	1
(hasComponent)	[Complex:74685] Insulin:p-6Y-Insulin receptor:p-Y427-SHC1 [plasma membrane] [Homo sapiens] [Complex:109798] GRB2-1:SOS1:p-Y427-SHC1 [cytosol] [Homo sapiens] [Complex:443900] Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] [Homo sapiens] [Complex:5686063] GRB2-1:p-4S-SOS1:p-Y427-SHC1 [cytosol] [Homo sapiens]
(input)	[Reaction:74746] GRB2-1:SOS1 binds p-Y427-SHC1 [Homo sapiens] [BlackBoxEvent:74748] De-phosphorylation of p-Y427-SHC1 [Homo sapiens]
(output)	[Reaction:74743] Dissociation of p-Y427-SHC1 from insulin receptor [Homo sapiens] [BlackBoxEvent:443910] SHC1 dissociates from integrin alphaIIb beta3 [Homo sapiens] [Reaction:5686074] GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9869610] Update Tracker - [EntityWithAccessionedSequence:74684] p-Y427-SHC1 [cytosol] - v34:[modifyName] [_UpdateTracker:9876645] Update Tracker - [EntityWithAccessionedSequence:74684] p-Y427-SHC1 [cytosol] - v44:[modifyEndCoordinate] [_UpdateTracker:9884406] Update Tracker - [EntityWithAccessionedSequence:74684] p-Y427-SHC1 [cytosol] - v45:[addName] [_UpdateTracker:9892501] Update Tracker - [EntityWithAccessionedSequence:74684] p-Y427-SHC1 [cytosol] - v53:[modifyName]
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No pathways have been reviewed or authored by p-Y427-SHC1 [cytosol] (74684)