Query author contributions in Reactome

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Details on Person SHC1 [cytosol]

Class:Id	EntityWithAccessionedSequence:74680
_displayName	SHC1 [cytosol]
_timestamp	2014-09-26 07:15:45
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:74677] Schmidt, EE, 2003-08-20 08:52:29
endCoordinate	583
modified	[InstanceEdit:77383] Schmidt, EE, 2003-10-24 07:52:24 [InstanceEdit:204777] Garapati, P V, 2007-12-03 09:53:12 [InstanceEdit:443899] Jupe, S, 2009-10-16 [InstanceEdit:453095] Jupe, S, 2010-01-18 [InstanceEdit:2685585] Garapati, P V, 2012-12-03 [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:5624358] Jupe, Steve, 2014-09-26
name	SHC1 SHC1 p66 SHC SHC transforming protein
referenceEntity	[ReferenceGeneProduct:64430] UniProt:P29353 SHC1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:367517] R-HSA-74680.1
startCoordinate	1
(activeUnit)	[CatalystActivity:9851159] transmembrane receptor protein tyrosine kinase adaptor activity of SHC1 [cytosol]
(hasComponent)	[Complex:74681] Insulin:p-6Y-Insulin receptor:SHC1 [plasma membrane] [Homo sapiens] [Complex:162549] SHC1:phospho-FRS2 [cytosol] [Homo sapiens] [Complex:180301] EGF:p-6Y-EGFR:SHC1 [plasma membrane] [Homo sapiens] [Complex:190392] Complex of Activated FGFR with SHC [plasma membrane] [Homo sapiens] [Complex:204857] ANGPT1:p-5Y,S119-TEK:SHC1 [plasma membrane] [Homo sapiens] [Complex:432098] Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] [Homo sapiens] [Complex:452095] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] [Homo sapiens] [Complex:912310] IL3:IL3R active complex, phosphorylated Bc:SHC1 [plasma membrane] [Homo sapiens] [Complex:913358] IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] [Homo sapiens] [Complex:913387] High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] [Homo sapiens] List all 44 refering instances
(hasMember)	[DefinedSet:167023] SHC [cytosol] [Homo sapiens] [DefinedSet:535579] Proteins Upregulated by XBP1(S) [cytosol] [Homo sapiens]
(input)	[Reaction:74740] Binding of SHC1 to insulin receptor [Homo sapiens] [BlackBoxEvent:162553] phospho-FRS2 binds to SHC protein [Homo sapiens] [Reaction:162562] Phosphorylation of SHC1 protein [Homo sapiens] [Reaction:177925] SHC1 binds to the phosphorylated EGF receptor:ligand complex [Homo sapiens] [Reaction:190391] SHC binds activated FGFR [Homo sapiens] [Reaction:204861] Interaction of Tie2 and Shc1 [Homo sapiens] [Reaction:432096] Activated integrin alphaIIb beta3 binds SHC1 [Homo sapiens] [Reaction:452091] Phosphorylation of IL2RB Y338 enables SHC recruitment [Homo sapiens] [Reaction:879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain [Homo sapiens] [Reaction:1225947] Binding of SHC1 to p-6Y-EGFR mutants [Homo sapiens] List all 27 refering instances
(output)	[BlackBoxEvent:74748] De-phosphorylation of p-Y427-SHC1 [Homo sapiens] [BlackBoxEvent:1791134] Expression of SHC1 [Homo sapiens]
(physicalEntity)	[CatalystActivity:9851159] transmembrane receptor protein tyrosine kinase adaptor activity of SHC1 [cytosol]
(updatedInstance)	[_UpdateTracker:9868401] Update Tracker - [EntityWithAccessionedSequence:74680] SHC1 [cytosol] - v31:[addName] [_UpdateTracker:9875943] Update Tracker - [EntityWithAccessionedSequence:74680] SHC1 [cytosol] - v44:[modifyEndCoordinate, modifyName] [_UpdateTracker:9882518] Update Tracker - [EntityWithAccessionedSequence:74680] SHC1 [cytosol] - v45:[addName]
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No pathways have been reviewed or authored by SHC1 [cytosol] (74680)