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Details on Person PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP

Class:IdReaction:74615
_displayNamePRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP
_doReleaseTRUE
_timestamp2013-05-31 09:35:40
authored[InstanceEdit:73925] Schmidt, EE, 2003-07-11 09:09:49
catalystActivity[CatalystActivity:74614] calcium,diacylglycerol-dependent serine/threonine kinase activity of PRKCA/Q [photoreceptor disc membrane]
compartment[Compartment:2514888] photoreceptor disc membrane
[Compartment:70101] cytosol
created[InstanceEdit:74965] Carleton, KL, 2003-07-31 08:44:54
edited[InstanceEdit:3270616] Jassal, B, 2013-04-11
inferredFrom
input[Complex:74601] RGS9-1:GNB5:RGS9BP [photoreceptor disc membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:2648982] Identification of protein kinase C isozymes responsible for the phosphorylation of photoreceptor-specific RGS9-1 at Ser475
[LiteratureReference:74622] Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments.
[LiteratureReference:74620] Phosphorylation of the regulator of G protein signaling RGS9-1 by protein kinase A is a potential mechanism of light- and Ca2+-mediated regulation of G protein function in photoreceptors.
modified[InstanceEdit:74964] Schmidt, EE, 2003-07-31 08:44:50
[InstanceEdit:2470272] Jassal, Bijay, 2012-09-18
[InstanceEdit:2648981] Jassal, Bijay, 2012-11-22
[InstanceEdit:3270611] Jassal, Bijay, 2013-04-11
[InstanceEdit:3632874] Jassal, Bijay, 2013-05-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP
PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP to form p-S478-RGS9-1:GN5B:RGS9BP
output[Complex:2648990] p-S478-RGS9-1:GNB5:RGS9BP [photoreceptor disc membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2013-06-11
reviewed[InstanceEdit:3270610] Makino, C, 2013-04-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3654184] R-HSA-74615.2
summation[Summation:2648992] In bovine experiments, phosphorylation of RGS9-1 (at Ser475,...
(hasEvent)[Pathway:74632] Gt-alpha-PDE* inactivation [Homo sapiens]
[Pathway:2514859] Inactivation, recovery and regulation of the phototransduction cascade [Homo sapiens]
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No pathways have been reviewed or authored by PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP (74615)