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Details on Person SLC35D2 exchanges UDP-GlcNAc for UMP

Class:Id	Reaction:744231
_displayName	SLC35D2 exchanges UDP-GlcNAc for UMP
_doRelease	TRUE
_timestamp	2025-03-14 09:05:17
authored	[InstanceEdit:744238] Jassal, Bijay, 2010-05-17
catalystActivity	[CatalystActivity:744232] nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane]
catalystActivityReference	[CatalystActivityReference:9792604] nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane] Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:744238] Jassal, Bijay, 2010-05-17
crossReference	[DatabaseIdentifier:9941483] RHEA:72695
edited	[InstanceEdit:744238] Jassal, Bijay, 2010-05-17
goBiologicalProcess	[GO_BiologicalProcess:25012] nucleotide-sugar transmembrane transport
input	[SimpleEntity:735698] UMP [Golgi lumen] [SimpleEntity:162756] UDP-GlcNAc [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:744226] Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection [LiteratureReference:744228] Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family
modified	[InstanceEdit:744882] Jassal, Bijay, 2010-05-18 [InstanceEdit:745609] Jassal, Bijay, 2010-05-18 [InstanceEdit:762751] Jassal, Bijay, 2010-05-20 [InstanceEdit:3508921] Jassal, Bijay, 2013-05-20 [InstanceEdit:9792605] D'Eustachio, Peter, 2022-05-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9941465] Stephan, Ralf, 2025-03-07 [InstanceEdit:9942322] Stephan, Ralf, 2025-03-14
name	SLC35D2 exchanges UDP-GlcNAc for UMP
output	[SimpleEntity:109402] UMP [cytosol] [SimpleEntity:914003] UDP-GlcNAc [Golgi lumen]
releaseDate	2010-06-15
reviewed	[InstanceEdit:706449] He, L, 2010-05-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105702] R-HSA-744231.4
summation	[Summation:744884] The human gene SLC35D2 encodes the UDP-N-acetylglucosamine/U...
(hasEvent)	[Pathway:727802] Transport of nucleotide sugars [Homo sapiens] [Pathway:2022854] Keratan sulfate biosynthesis [Homo sapiens] [Pathway:2022928] HS-GAG biosynthesis [Homo sapiens]
(precedingEvent)	[Reaction:2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain [Homo sapiens] [Reaction:2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG [Homo sapiens] [Reaction:9953259] EXTL3 dimer transfers GlcNAc to the GAG linker [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787459] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-sugars for UMP - v45:[modifyText] [_UpdateTracker:9847051] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-GlcNAc for UMP - v82:[add_removeInput, add_removeOutput, modifyText] [_UpdateTracker:9953558] Update Tracker - [Reaction:744231] SLC35D2 exchanges UDP-GlcNAc for UMP - v93:[modifyText]
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