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Details on Person CALM1:4xCa2+ [cytosol]
Class:Id Complex:74294
_displayName CALM1:4xCa2+ [cytosol]
_timestamp 2017-08-15 13:33:19
compartment [Compartment:70101] cytosol
created [InstanceEdit:74292] Schmidt, EE, 2003-07-18 12:05:45
hasComponent
literatureReference [LiteratureReference:74025] Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation.
modified [InstanceEdit:74429] Schmidt, EE, 2003-07-22 11:02:16 [InstanceEdit:111852] Schmidt, EE, 2004-03-24 06:49:11 [InstanceEdit:201796] Jassal, Bijay, 2007-09-20 [InstanceEdit:5339581] Jassal, B, 2014-03-06 [InstanceEdit:6793944] Jassal, Bijay, 2015-09-04 [InstanceEdit:9016713] Jassal, Bijay, 2017-08-15 [InstanceEdit:9016719] Jassal, Bijay, 2017-08-15
name CALM1:4xCa2+ Active Calmodulin
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:366728] R-HSA-74294.3
(hasComponent) [Complex:74017] Calmodulin - associated open cGMP-gated ion channel [plasma membrane] [Homo sapiens] [Complex:74431] Calmodulin-associated channel [plasma membrane] [Homo sapiens] [Complex:111965] GRK2:CALM1:4xCa2+ [plasma membrane] [Homo sapiens] [Complex:201762] PPP3CA,B,C:Fe3+:Zn2+:4xCa2+:CaM [cytosol] [Homo sapiens] [Complex:202121] p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] [Homo sapiens] [Complex:376013] MLCK:Calmodulin [plasma membrane] [Homo sapiens] [Complex:420430] Adducin beta:active calmodulin [cytosol] [Homo sapiens] [Complex:442735] Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] [Homo sapiens] [Complex:444601] CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] [Homo sapiens] [Complex:445764] MYLK:Ca2+:CALM1 [cytosol] [Homo sapiens]
(input) [Reaction:111892] Ca(4)CaM => Calmodulin + 4 Ca2+ [Homo sapiens] [Reaction:111966] GRK2 binds CALM1:4Ca2+ [Homo sapiens] [Reaction:201783] Inactive catalytic PP2B is activated by the binding of calmodulin [Homo sapiens] [Reaction:202110] eNOS:Caveolin-1 complex binds to CaM [Homo sapiens] [Reaction:376133] MLCK binds Ca++:calmodulin [Homo sapiens] [Reaction:426307] Adducin binds calmodulin [Homo sapiens] [Reaction:442725] CaMKII binds activated calmodulin [Homo sapiens] [Reaction:442760] Activation of RasGRF [Homo sapiens] [Reaction:445797] MYLK (MLCK) Active Calmodulin Binding [Homo sapiens] [Reaction:2025890] Calcineurin binds NFATC1,2,3 [Homo sapiens]
(output) [Reaction:74448] Calcium binds calmodulin [Homo sapiens] [Reaction:202129] HSP90 binds eNOS:Caveolin-1:CaM complex [Homo sapiens] [Reaction:4332358] Dissociation of CaM and CAMK2 autophosphorylation [Homo sapiens] [Reaction:9618811] Calcium binds calmodulin at the synapse [Homo sapiens] [BlackBoxEvent:9654533] KRAS4B recycles to the plasma membrane [Homo sapiens]
(regulator) [PositiveRegulation:1489501] Positive regulation by 'CALM1:4xCa2+ [cytosol]' [PositiveRegulation:9034487] Positive regulation by 'CALM1:4xCa2+ [cytosol]'
(replacementInstances) [_Deleted:9615331] Deletion of instance: 194447
(updatedInstance) [_UpdateTracker:9889406] Update Tracker - [Complex:74294] CALM1:4xCa2+ [cytosol] - v49:[modifyName] [_UpdateTracker:9893079] Update Tracker - [Complex:74294] CALM1:4xCa2+ [cytosol] - v55:[modifyName] [_UpdateTracker:9897487] Update Tracker - [Complex:74294] CALM1:4xCa2+ [cytosol] - v62:[add_removeHasComponent]
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No pathways have been reviewed or authored by CALM1:4xCa2+ [cytosol] (74294)