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Details on Person dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)

Class:IdReaction:74207
_displayNamedA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)
_doReleaseTRUE
_timestamp2025-12-16 18:01:39
catalystActivity[CatalystActivity:74206] deoxynucleoside kinase activity of DGUOK dimer [mitochondrial matrix]
catalystActivityReference[CatalystActivityReference:9643208] nucleoside kinase activity of DGUOK dimer [mitochondrial matrix] Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:74183] Jassal, B, 2003-07-17 08:31:43
crossReference[DatabaseIdentifier:9976237] RHEA:23453
[DatabaseIdentifier:9976221] RHEA:19202
input[DefinedSet:500224] dA, dG, dI [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
internalReviewed[InstanceEdit:9977060] D'Eustachio, Peter, 2025-12-16
literatureReference[LiteratureReference:109711] Cloning and expression of human deoxyguanosine kinase cDNA
[LiteratureReference:109719] Properties of a highly purified mitochondrial deoxyguanosine kinase
[LiteratureReference:109712] Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
modified[InstanceEdit:74479] D'Eustachio, P, 2003-07-22 16:21:00
[InstanceEdit:76579] D'Eustachio, P, 2003-10-11 14:30:00
[InstanceEdit:109706] D'Eustachio, P, 2004-01-20 11:10:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:500223] D'Eustachio, P, 2010-02-01
[InstanceEdit:500228] D'Eustachio, P, 2010-02-01
[InstanceEdit:504063] D'Eustachio, P, 2010-02-05
[InstanceEdit:504071] D'Eustachio, P, 2010-02-07
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:8956390] D'Eustachio, Peter, 2017-01-22
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9976255] D'Eustachio, Peter, 2025-12-09
[InstanceEdit:9977061] D'Eustachio, Peter, 2025-12-16
[InstanceEdit:9977063] D'Eustachio, Peter, 2025-12-16
namedA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)
2'-deoxyadenosine + ATP => dAMP + ADP + H(+)
2'-deoxyguanosine + ATP => dGMP + ADP + H(+)
output[DefinedSet:500222] dAMP, dGMP, dIMP [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113529] H+ [mitochondrial matrix]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2004-07-06
reviewed[InstanceEdit:9977064] D'Eustachio, Peter, 2025-12-16
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361647] R-HSA-74207.6
structureModified[InstanceEdit:9976255] D'Eustachio, Peter, 2025-12-09
summation[Summation:178290] Mitochondrial deoxyguanosine kinase (DGUOK) catalyzes the re...
(hasEvent)[Pathway:74217] Purine salvage [Homo sapiens]
(precedingEvent)[Reaction:73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1) [Homo sapiens]
(replacementInstances)[_Deleted:500225] Deletion of instances: 109733, 109708
[_Deleted:500227] Deletion of instance: 109709
(updatedInstance)[_UpdateTracker:9790820] Update Tracker - [Reaction:74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - v32:[add_removeInput, add_removeLiteratureReference, add_removeOutput, modifyText]
[_UpdateTracker:9984567] Update Tracker - [Reaction:74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - v96:[removeOutput]
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