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Details on Person SLC35A3 exchanges UDP-GlcNAc for UMP

Class:Id	Reaction:741450
_displayName	SLC35A3 exchanges UDP-GlcNAc for UMP
_doRelease	TRUE
_timestamp	2014-12-01 16:00:05
authored	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
catalystActivity	[CatalystActivity:741455] UDP-N-acetylglucosamine transmembrane transporter activity of SLC35A3 [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen [Compartment:70101] cytosol
created	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
edited	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
input	[SimpleEntity:162756] UDP-GlcNAc [cytosol] [SimpleEntity:735698] UMP [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:741451] Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter
modified	[InstanceEdit:745609] Jassal, Bijay, 2010-05-18 [InstanceEdit:762751] Jassal, Bijay, 2010-05-20 [InstanceEdit:1475045] Jassal, Bijay, 2011-08-08 [InstanceEdit:3903036] Jassal, Bijay, 2013-07-17 [InstanceEdit:5653590] Jassal, Bijay, 2014-12-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SLC35A3 exchanges UDP-GlcNAc for UMP
output	[SimpleEntity:914003] UDP-GlcNAc [Golgi lumen] [SimpleEntity:109402] UMP [cytosol]
releaseDate	2010-06-15
reviewed	[InstanceEdit:706449] He, L, 2010-05-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104100] R-HSA-741450.2
summation	[Summation:741445] The human gene SLC35A3 encodes a UDP-GlcNAc transporter (Ish...
(hasEvent)	[Pathway:727802] Transport of nucleotide sugars [Homo sapiens]
(normalReaction)	[FailedReaction:5653622] Defective SLC35A3 does not exchange UDP-GlcNAc for UMP [Homo sapiens]
(precedingEvent)	[Reaction:2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain [Homo sapiens] [Reaction:2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG [Homo sapiens] [Reaction:9953259] EXTL3 dimer transfers GlcNAc to the GAG linker [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785550] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v52:[modifyText] [_UpdateTracker:9787089] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v46:[add_removeInput] [_UpdateTracker:9789170] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v38:[add_removeOutput]
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