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Details on Person Ca2+ [extracellular region]
| Class:Id | SimpleEntity:74112 |
| _displayName | Ca2+ [extracellular region] |
| _timestamp | 2016-02-22 22:14:09 |
| compartment | [Compartment:984] extracellular region |
| crossReference | [DatabaseIdentifier:29497] COMPOUND:C00076 |
| modified | [InstanceEdit:74163] Joshi-Tope, G, 2003-07-15 16:33:00 [InstanceEdit:1498719] Williams, MG, 2011-08-17 [InstanceEdit:2534374] Gillespie, ME, 2012-10-25 [InstanceEdit:2562608] D'Eustachio, P, 2012-11-06 [InstanceEdit:3295578] Jassal, Bijay, 2013-04-17 [InstanceEdit:3605680] Jassal, B, 2013-05-23 [InstanceEdit:8852519] Jupe, Steve, 2016-01-19 [InstanceEdit:8861981] Matthews, Lisa, 2016-02-22 [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619952] Wu, G, 2018-09-19 |
| name | Ca2+ Calcium calcium(2+) |
| referenceEntity | [ReferenceMolecule:114768] calcium(2+) [ChEBI:29108] |
| stableIdentifier | [StableIdentifier:363887] R-ALL-74112.4 |
| (hasComponent) | [Complex:140689] factor Xa [extracellular region] [Homo sapiens] [Complex:140692] factor Va [extracellular region] [Homo sapiens] [Complex:140751] factor VIIa:Ca2+ [extracellular region] [Homo sapiens] [Complex:140849] factor XIIIa [extracellular region] [Homo sapiens] [Complex:141050] Activated protein C [extracellular region] [Homo sapiens] [Complex:156786] activated thrombin (factor IIa) [extracellular region] [Homo sapiens] [Complex:166719] MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane] [Homo sapiens] [Complex:166724] MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] [Homo sapiens] [Complex:188976] alpha-amylase 1B, salivary [extracellular region] [Homo sapiens] [Complex:189012] alpha-amylase 2B, pancreatic [extracellular region] [Homo sapiens] |
| (hasMember) | [CandidateSet:377604] Integrin binding divalent cations [extracellular region] [DefinedSet:420706] GPRC6A ligands [extracellular region] [DefinedSet:426219] Cations [extracellular region] [DefinedSet:481030] Platelet dense granule content [extracellular region] [Homo sapiens] [DefinedSet:790906] Ligands of GPCRs that activate Gi [extracellular region] [Homo sapiens] [DefinedSet:791492] Ligands of GPCRs that activate Gq/11 [extracellular region] [Homo sapiens] [DefinedSet:8850849] Ca2+,Mg2+ [extracellular region] [DefinedSet:9855128] Ca2+,K+,Mg2+,Na+ [extracellular region] |
| (input) | [Reaction:114578] Ca++ entry from plasma [Homo sapiens] [Reaction:139855] P2X1-mediated entry of Ca++ from plasma [Homo sapiens] [Reaction:140736] OBSOLETE_factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)_REPLACEMENT_9822514 [Homo sapiens] [Reaction:140847] factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain [Homo sapiens] [Reaction:158164] factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) [Homo sapiens] [Reaction:166721] MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa [Homo sapiens] [Reaction:202005] Formation of cadherin junctions [Homo sapiens] [Reaction:202017] Formation of cadherin lateral dimers [Homo sapiens] [Reaction:210420] Ca2+ influx through voltage gated Ca2+ channels [Homo sapiens] [Reaction:264563] Calcium Influx through Voltage-gated Calcium Channels [Mus musculus] |
| (output) | [BlackBoxEvent:265166] Exocytosis of Insulin [Homo sapiens] [Reaction:418309] ATP2B1-4 transport cytosolic Ca2+ to extracellular region [Homo sapiens] [Reaction:425661] SLC8A1,2,3 exchange 3Na+ for Ca2+ [Homo sapiens] [Reaction:425678] SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ [Homo sapiens] [Reaction:425822] K+-independent Li+/Ca2+ exchanger transport [Homo sapiens] [Reaction:426913] Efflux of Na+/Ca2+ ions from the cytosol to the extracellular region [Drosophila melanogaster] [Reaction:2514891] SLC24A1 exchanges 4Na+ for Ca2+, K+ [Homo sapiens] [Reaction:2534148] Nckx1 exchanges Na+ for Ca2+/K+ [Bos taurus] [Reaction:9662114] ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region [Homo sapiens] [Reaction:9664214] ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region [Homo sapiens] |
| (regulator) | [PositiveRegulation:158643] Positive regulation by 'Ca2+ [extracellular region]' [PositiveRegulation:158645] Positive regulation by 'Ca2+ [extracellular region]' |
| (replacementInstances) | [_Deleted:5205619] Deletion of instance: 3465605 |
| (requiredInputComponent) | [Reaction:140686] factor Va + factor Xa -> Va:Xa complex (prothrombinase) [Homo sapiens] |
| (updatedInstance) | [_UpdateTracker:9890921] Update Tracker - [SimpleEntity:74112] Ca2+ [extracellular region] - v52:[addName] |
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No pathways have been reviewed or authored by Ca2+ [extracellular region] (74112)