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Details on Person Resynthesis of excised residue by POLB

Class:Id	Reaction:73932
_displayName	Resynthesis of excised residue by POLB
_doRelease	TRUE
_timestamp	2017-04-28 15:49:02
authored	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
catalystActivity	[CatalystActivity:5649635] DNA-directed DNA polymerase activity of LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input	[Complex:110339] LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] [Homo sapiens] [SimpleEntity:30555] dNTP [nucleoplasm]
literatureReference	[LiteratureReference:111257] Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
modified	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00 [InstanceEdit:111239] Matthews, L, 2004-02-09 03:00:00 [InstanceEdit:111316] Matthews, L, 2004-02-11 20:00:00 [InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:5649639] Orlic-Milacic, Marija, 2014-11-20 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:8986535] Orlic-Milacic, Marija, 2017-04-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Resynthesis of excised residue by POLB
output	[SimpleEntity:113541] PPi [nucleoplasm] [Complex:110341] LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB [Homo sapiens] [Reaction:110375] Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:362071] R-HSA-73932.3
summation	[Summation:110378] POLB (DNA polymerase beta) mediates DNA synthesis that fills...
(hasEvent)	[Pathway:110381] Resolution of AP sites via the single-nucleotide replacement pathway [Homo sapiens]
(precedingEvent)	[Reaction:73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784888] Update Tracker - [Reaction:73932] Resynthesis of excised residue by POLB - v52:[add_removeCatalystActivity, modifyText] [_UpdateTracker:9785700] Update Tracker - [Reaction:73932] Resynthesis of excised residue by POLB - v51:[modifyText]
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