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Details on Person Binding of RRN3 to RNA Polymerase I

Class:Id	Reaction:73757
_displayName	Binding of RRN3 to RNA Polymerase I
_doRelease	TRUE
_timestamp	2026-05-06 19:05:30
authored	[InstanceEdit:75829] Gillespie, ME, 2003-09-02 00:00:00
compartment	[Compartment:7660] nucleoplasm
edited	[InstanceEdit:165085] Gillespie, ME, 0000-00-00 00:00:00
figure	[Figure:75833] /figures/PolI_txn_Rrn3BindsRNAPolI.jpg
input	[Complex:73859] RNA Polymerase I Holoenzyme [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:73714] RRN3 [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:8984057] RNA polymerase I-Rrn3 complex at 4.8 � resolution [LiteratureReference:8984049] Structure of the initiation-competent RNA polymerase I and its implication for transcription [LiteratureReference:73759] Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. [LiteratureReference:9988053] hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters
modified	[InstanceEdit:73862] Gillespie, ME, 2003-07-03 00:00:00 [InstanceEdit:73862] Gillespie, ME, 2003-07-03 00:00:00 [InstanceEdit:75829] Gillespie, ME, 2003-09-02 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:5419295] May, Bruce, 2014-05-04 [InstanceEdit:5419296] May, Bruce, 2014-05-04 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8984052] Varusai, Thawfeek, 2017-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9988361] Rothfels, Karen, 2026-05-06
name	Binding of RRN3 to RNA Polymerase I
output	[Complex:73715] Active RNA Polymerase I [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:73865] Assembly of RNA Polymerase I holoenzyme [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360471] R-HSA-73757.4
summation	[Summation:75841] After the assembly of the RNA Pol I holoenzyme, RRN3 binding...
(hasEvent)	[Pathway:73762] RNA Polymerase I Transcription Initiation [Homo sapiens]
(inferredFrom)	[Reaction:1113262] Binding of Rrn3 to RNA Polymerase I [Oryza sativa]
(orthologousEvent)	[Reaction:1113262] Binding of Rrn3 to RNA Polymerase I [Oryza sativa]
(precedingEvent)	[Reaction:73758] Recruitment of RNA Polymerase I:RRN3 to the 45S pre-rRNA gene [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781212] Update Tracker - [Reaction:73757] Binding of RRN3 to RNA Polymerase I - v61:[addLiteratureReference, modifyText]
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