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Details on Person Phosphorylation of UBTF

Class:IdReaction:73722
_displayNamePhosphorylation of UBTF
_doReleaseTRUE
_timestamp2026-05-14 20:17:48
authored[InstanceEdit:73851] Comai, L, 2003-07-03 17:13:29
catalystActivity[CatalystActivity:164955] MAP kinase activity of p-T202, Y204 MAPK3 dimer [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:73851] Comai, L, 2003-07-03 17:13:29
edited[InstanceEdit:165085] Gillespie, ME, 0000-00-00 00:00:00
input[SimpleEntity:29358] ATP [nucleoplasm]
[Complex:9988363] UBTF:45S pre-rRNA gene [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9989056] Gillespie, Marc E, 2026-05-14
literatureReference[LiteratureReference:73725] An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF.
modified[InstanceEdit:73849] Gillespie, ME, 2003-07-01 00:00:00
[InstanceEdit:83531] Gillespie, ME, 2003-11-13 00:00:00
[InstanceEdit:109689] Gillespie, ME, 2004-01-19 00:00:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:164957] Gillespie, ME, 2005-07-22 21:24:53
[InstanceEdit:166242] Gillespie, ME, 2005-08-22 20:58:52
[InstanceEdit:202102] D'Eustachio, P, 2007-10-18 14:15:25
[InstanceEdit:211334] D'Eustachio, P, 2008-01-31 21:04:16
[InstanceEdit:5419295] May, Bruce, 2014-05-04
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9616355] Gillespie, Marc E, 2018-08-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9988367] Rothfels, Karen, 2026-05-06
[InstanceEdit:9989077] Rothfels, Karen, 2026-05-14
namePhosphorylation of UBTF
output[Complex:73685] p-UBTF:45S pre-rRNA gene [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821385] four stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359590] R-HSA-73722.4
structureModified[InstanceEdit:9988367] Rothfels, Karen, 2026-05-06
summation[Summation:73727] Phosphorylation of promoter-bound UBTF activates it, enablin...
(hasEvent)[Pathway:73728] RNA Polymerase I Promoter Opening [Homo sapiens]
(precedingEvent)[Reaction:73739] Recruitment of acetylated SL1 to p-UBTF:45S pre-rRNA gene [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779225] Update Tracker - [Reaction:73722] Phosphorylation of UBF-1:rDNA Promoter - v66:[addOutput]
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