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Details on Person 2xHC-TXN [cytosol]

Class:Id	EntityWithAccessionedSequence:73668
_displayName	2xHC-TXN [cytosol]
_timestamp	2020-04-29 01:26:34
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:73446] Jassal, B, 2003-06-17 09:00:25
endCoordinate	105
hasModifiedResidue	[IntraChainCrosslinkedResidue:111706] Intra-chain Crosslink via L-cystine (cross-link) at 32 and 35
modified	[InstanceEdit:74394] D'Eustachio, P, 2003-07-21 13:51:00 [InstanceEdit:111698] D'Eustachio, P, 2004-03-17 17:27:00 [InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08 [InstanceEdit:1250252] Jupe, S, 2011-04-15 [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3322333] Wu, G, 2013-05-03 [InstanceEdit:3322334] Wu, G, 2013-05-03 [InstanceEdit:9686253] May, Bruce, 2020-04-29
name	2xHC-TXN Thioredoxin, oxidized Thioredoxin ATL-derived factor ADF Surface associated sulphydryl protein SASP
referenceEntity	[ReferenceGeneProduct:66001] UniProt:P10599 TXN [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:366846] R-HSA-73668.2
startCoordinate	2
(hasComponent)	[Complex:1250249] Oxidized thioredoxin:TXNIP [cytosol] [Homo sapiens]
(input)	[Reaction:73646] Regeneration of active (reduced) Thioredoxin [Homo sapiens]
(output)	[Reaction:111751] RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) [Homo sapiens] [Reaction:111804] RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) [Homo sapiens] [Reaction:1250253] TXNIP is released from oxidized thioredoxin [Homo sapiens] [BlackBoxEvent:1250280] ROS oxidize thioredoxin [Homo sapiens] [Reaction:3225851] ROS oxidize thioredoxin and activate MAP3K5 [Homo sapiens] [Reaction:3341343] PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O [Homo sapiens] [Reaction:3697882] PRDX5 reduces peroxynitrite to nitrite using TXN [Homo sapiens] [Reaction:5676917] MRSBs reduce L-methyl-(R)-S-oxide to L-methionine [Homo sapiens] [Reaction:5676940] MSRA reduces L-methyl-(S)-S-oxide to L-Methionine [Homo sapiens]
(replacementInstances)	[_Deleted:8866415] Deletion of instance: 111802
(updatedInstance)	[_UpdateTracker:9870096] Update Tracker - [EntityWithAccessionedSequence:73668] 2xHC-TXN [cytosol] - v37:[modifyName] [_UpdateTracker:9878407] Update Tracker - [EntityWithAccessionedSequence:73668] 2xHC-TXN [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9886831] Update Tracker - [EntityWithAccessionedSequence:73668] 2xHC-TXN [cytosol] - v45:[addName] [_UpdateTracker:9901226] Update Tracker - [EntityWithAccessionedSequence:73668] 2xHC-TXN [cytosol] - v73:[removeHasModifiedResidue]
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No pathways have been reviewed or authored by 2xHC-TXN [cytosol] (73668)