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Details on Person dCMP + H2O => dUMP + NH4+

Class:IdReaction:73596
_displayNamedCMP + H2O => dUMP + NH4+
_doReleaseTRUE
_timestamp2025-12-09 20:34:51
catalystActivity[CatalystActivity:73593] dCMP deaminase activity of DCTD hexamer [cytosol]
catalystActivityReference[CatalystActivityReference:9643880] dCMP deaminase activity of DCTD hexamer [cytosol] Properties of an affinity-column-purified human deoxycytidylate deaminase
compartment[Compartment:70101] cytosol
created[InstanceEdit:73446] Jassal, B, 2003-06-17 09:00:25
crossReference[DatabaseIdentifier:9976227] RHEA:22925
input[SimpleEntity:109378] dCMP [cytosol]
[SimpleEntity:29356] H2O [cytosol]
[SimpleEntity:70106] H+ [cytosol]
literatureReference[LiteratureReference:200103] Primary structure of human deoxycytidylate deaminase and overexpression of its functional protein in Escherichia coli
[LiteratureReference:500734] Properties of an affinity-column-purified human deoxycytidylate deaminase
modified[InstanceEdit:73832] Jassal, B, 2003-07-03 08:48:35
[InstanceEdit:74362] D'Eustachio, P, 2003-07-18 15:39:00
[InstanceEdit:74394] D'Eustachio, P, 2003-07-21 13:51:00
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:200032] D'Eustachio, P, 2007-07-13 20:48:01
[InstanceEdit:500731] D'Eustachio, P, 2010-02-04
[InstanceEdit:504063] D'Eustachio, P, 2010-02-05
[InstanceEdit:504071] D'Eustachio, P, 2010-02-07
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:8956316] D'Eustachio, Peter, 2017-01-20
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9737460] D'Eustachio, Peter, 2021-07-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9976236] D'Eustachio, Peter, 2025-12-09
namedCMP + H2O => dUMP + NH4+
dCMP + H2O + H(+) => dUMP + NH4(+)
deamination of dCMP to form dUMP
output[SimpleEntity:109382] dUMP [cytosol]
[SimpleEntity:31633] NH4+ [cytosol]
precedingEvent
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361579] R-HSA-73596.7
summation[Summation:178288] Cytosolic deoxycytidylate deaminase (DCTD) catalyzes the hyd...
(hasEvent)[Pathway:499943] Interconversion of nucleotide di- and triphosphates [Homo sapiens]
(precedingEvent)[Reaction:73605] conversion of dUMP to dTMP [Homo sapiens]
[Reaction:73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775602] Update Tracker - [Reaction:73596] dCMP + H2O => dUMP + NH4+ - v78:[addInput]
[_UpdateTracker:9781683] Update Tracker - [Reaction:73596] dCMP + H2O => dUMP + NH4+ - v60:[add_removeOutput]
[_UpdateTracker:9790850] Update Tracker - [Reaction:73596] dCMP + H2O => dUMP + NH4+ - v32:[addLiteratureReference, modifyText]
[_UpdateTracker:9792349] Update Tracker - [Reaction:73596] dCMP + H2O => dUMP + NH4+ - v22:[addLiteratureReference]
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