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Details on Person SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP

Class:Id	Reaction:735702
_displayName	SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP
_doRelease	TRUE
_timestamp	2014-11-27 15:52:35
authored	[InstanceEdit:735694] Jassal, Bijay, 2010-05-13
catalystActivity	[CatalystActivity:735696] UDP-galactose transmembrane transporter activity of SLC35A2 [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen [Compartment:70101] cytosol
created	[InstanceEdit:735694] Jassal, Bijay, 2010-05-13
edited	[InstanceEdit:735694] Jassal, Bijay, 2010-05-13
input	[DefinedSet:735692] UDP-Gal, UDP-GalNAc [cytosol] [SimpleEntity:735698] UMP [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:735701] Human UDP-galactose translocator: molecular cloning of a complementary DNA that complements the genetic defect of a mutant cell line deficient in UDP-galactose translocator [LiteratureReference:735695] Human and Drosophila UDP-galactose transporters transport UDP-N-acetylgalactosamine in addition to UDP-galactose
modified	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14 [InstanceEdit:745609] Jassal, Bijay, 2010-05-18 [InstanceEdit:762751] Jassal, Bijay, 2010-05-20 [InstanceEdit:5652118] Jassal, Bijay, 2014-11-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP
output	[SimpleEntity:109402] UMP [cytosol] [DefinedSet:735691] UDP-Gal, UDP-GalNAc [Golgi lumen]
releaseDate	2010-06-15
reviewed	[InstanceEdit:706449] He, L, 2010-05-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104203] R-HSA-735702.2
summation	[Summation:735681] The human gene SLC35A2 encodes the UDP-galactose transporter...
(hasEvent)	[Pathway:727802] Transport of nucleotide sugars [Homo sapiens]
(normalReaction)	[FailedReaction:5652099] Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP [Homo sapiens]
(precedingEvent)	[Reaction:1889978] B3GALT6 transfers Gal to the tetrasaccharide linker [Homo sapiens] [Reaction:1889981] B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker [Homo sapiens] [Reaction:1971482] CSGALNACTs transfer GalNAc to CS linker glycan [Homo sapiens] [Reaction:1971487] Chondroitin polymerase complex transfers GalNAc to CS chain [Homo sapiens] [Reaction:2025723] B4GALTs transfer Gal to the N-glycan precursor [Homo sapiens] [Reaction:2046265] B4GALTs transfer Gal to the keratan chain [Homo sapiens] [Reaction:2046298] B4GALTs transfer Gal to a branch of keratan [Homo sapiens] [Reaction:5653878] B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac [Homo sapiens] [Reaction:9632033] CSGALNACTs transfer GalNAc to CS chain [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785178] Update Tracker - [Reaction:735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - v52:[modifyText]
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