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Details on Person (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1)

Class:Id	Reaction:73548
_displayName	(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1)
_doRelease	TRUE
_timestamp	2025-12-04 01:21:29
catalystActivity	[CatalystActivity:73495] nucleoside monophosphate kinase activity of CMPK1, AK1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643747] nucleoside monophosphate kinase activity of CMPK1, AK1 [cytosol] Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates.
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:73446] Jassal, B, 2003-06-17 09:00:25
crossReference	[DatabaseIdentifier:9975774] RHEA:25095 [DatabaseIdentifier:9975769] RHEA:11601 [DatabaseIdentifier:9975908] RHEA:24401
input	[DefinedSet:500009] (d)CMP, UMP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:74569] Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates. [LiteratureReference:110112] Kinetics and equilibria of pyrimidine nucleoside monophosphate kinase from human erythrocytes
modified	[InstanceEdit:73832] Jassal, B, 2003-07-03 08:48:35 [InstanceEdit:74394] D'Eustachio, P, 2003-07-21 13:51:00 [InstanceEdit:74479] D'Eustachio, P, 2003-07-22 16:21:00 [InstanceEdit:75119] D'Eustachio, P, 2003-08-25 12:00:00 [InstanceEdit:110076] D'Eustachio, P, 2004-01-28 17:55:00 [InstanceEdit:110253] D'Eustachio, P, 0000-00-00 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:499929] D'Eustachio, P, 2010-01-29 [InstanceEdit:500007] D'Eustachio, P, 2010-01-29 [InstanceEdit:500762] D'Eustachio, P, 2010-02-04 [InstanceEdit:504063] D'Eustachio, P, 2010-02-05 [InstanceEdit:504071] D'Eustachio, P, 2010-02-07 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8956390] D'Eustachio, Peter, 2017-01-22 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9975916] D'Eustachio, Peter, 2025-12-04
name	(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) dCMP + ATP => dCDP + ADP CMP + ATP => CDP + ADP UMP + ATP => UDP + ADP
output	[DefinedSet:500006] (d)CDP, UDP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:73598] (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) [Homo sapiens] [Reaction:73564] UMPS dimer decarboxylates OMP to UMP [Homo sapiens] [Reaction:73567] UMPS dimer transfers phosphoribosyl group to ORO to form OMP [Homo sapiens] [Reaction:73599] cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] [Homo sapiens]
releaseDate	2004-07-06
reverseReaction	[Reaction:75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) [Homo sapiens] [Reaction:73548] (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) [Homo sapiens]
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361731] R-HSA-73548.7
summation	[Summation:499938] Cytosolic UMP-CMP kinase (CMPK1) catalyzes the reversible re...
(hasEvent)	[Pathway:499943] Interconversion of nucleotide di- and triphosphates [Homo sapiens]
(precedingEvent)	[Reaction:482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) [Homo sapiens]
(replacementInstances)	[_Deleted:500010] Deletion of instances: 73627, 73623 [_Deleted:500015] Deletion of instance: 110107
(reverseReaction)	[Reaction:75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791039] Update Tracker - [Reaction:73548] (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) - v32:[add_removeInput, add_removeOutput, add_removeSummation]
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No pathways have been reviewed or authored by (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (73548)