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Pathways reviewed by Hinnebusch, Alan G (72712)
Details on Person Hinnebusch, Alan G
| Class:Id | Person:72712 |
| _displayName | Hinnebusch, Alan G |
| _timestamp | 2016-07-20 19:17:11 |
| affiliation | [Affiliation:1243085] National Institutes of Health,National Institute of Child Health and Human Development |
| firstname | Alan G |
| initial | AG |
| modified | [InstanceEdit:1243087] D'Eustachio, P, 2011-03-31 [InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20 |
| surname | Hinnebusch |
| (author) | [InstanceEdit:165086] Hershey, JW, Sonenberg, N, Hinnebusch, AG, 0000-00-00 00:00:00 [LiteratureReference:72708] A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo [LiteratureReference:212880] A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II [LiteratureReference:376968] eIF3: a versatile scaffold for translation initiation complexes [LiteratureReference:5672805] Regulation of translation initiation in eukaryotes: mechanisms and biological targets [LiteratureReference:8985208] The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors [LiteratureReference:8985425] The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly [LiteratureReference:9633756] A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2 [LiteratureReference:9633860] Interaction between the tRNA-binding and C-terminal domains of Yeast Gcn2 regulates kinase activity in vivo [LiteratureReference:9633871] Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation |
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