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Details on Person eIF5B:GTP is hydrolyzed and released

Class:Id	Reaction:72671
_displayName	eIF5B:GTP is hydrolyzed and released
_doRelease	TRUE
_timestamp	2016-11-10 00:56:29
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:72607] Merrick, WC, 2002-12-16 00:00:00
input	[Complex:72504] 80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:72715] The joining of ribosomal subunits in eukaryotes requires eIF5B [LiteratureReference:72719] Purification and characterization of homogeneous initiation factor M2A from rabbit reticulocytes
modified	[InstanceEdit:113852] Joshi-Tope, G, 2004-06-23 21:17:01 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2656454] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	eIF5B:GTP is hydrolyzed and released
output	[Complex:72502] eIF5B:GDP [cytosol] [Homo sapiens] [Complex:72505] 80S:Met-tRNAi:mRNA [cytosol] [Homo sapiens] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:72672] The 60S subunit joins the translation initiation complex [Homo sapiens] [Reaction:72673] Release of 40S and 60S subunits from the 80S ribosome [Homo sapiens] [Reaction:72619] eIF2:GTP is hydrolyzed, eIFs are released [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359211] R-HSA-72671.3
summation	[Summation:72740] Once the 60S subunit joins the translation initiation comple...
(hasEvent)	[Pathway:72706] GTP hydrolysis and joining of the 60S ribosomal subunit [Homo sapiens]
(precedingEvent)	[Reaction:156907] Aminoacyl-tRNA binds to the ribosome at the A-site [Homo sapiens]
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No pathways have been reviewed or authored by eIF5B:GTP is hydrolyzed and released (72671)