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Details on Person Formation of the cap-binding eIF4F complex

Class:Id	Reaction:72631
_displayName	Formation of the cap-binding eIF4F complex
_doRelease	TRUE
_timestamp	2016-11-10 00:56:53
compartment	[Compartment:70101] cytosol
input	[Complex:72576] eIF4A subunits complex [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72578] EIF4E [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72584] EIF4G1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:72632] The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A
modified	[InstanceEdit:110066] Joshi-Tope, G, 2004-01-26 13:16:45 [InstanceEdit:163156] Gopinathrao, G, 2005-04-20 15:59:42 [InstanceEdit:163176] Gopinathrao, G, 2005-04-20 18:31:08 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of the cap-binding eIF4F complex
output	[Complex:72587] eIF4F [cytosol] [Homo sapiens]
precedingEvent	[Reaction:72622] Release of eIF4E from the inactive eIF4E:4E-BP complex [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361482] R-HSA-72631.3
summation	[Summation:72634] eIF4A interacts with eIF4G, and eIF4E interacts with the ami...
(hasEvent)	[Pathway:72662] Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S [Homo sapiens]
(inferredFrom)	[Reaction:1113118] Formation of the cap-binding eIF4F complex [Oryza sativa]
(orthologousEvent)	[Reaction:1113118] Formation of the cap-binding eIF4F complex [Oryza sativa]
(precedingEvent)	[Reaction:72635] eIF4F binds to mRNP [Homo sapiens]
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No pathways have been reviewed or authored by Formation of the cap-binding eIF4F complex (72631)