Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person Release of eIF4E from the inactive eIF4E:4E-BP complex

Class:IdReaction:72622
_displayNameRelease of eIF4E from the inactive eIF4E:4E-BP complex
_doReleaseTRUE
_timestamp2016-11-10 00:56:55
compartment[Compartment:70101] cytosol
input[Complex:72581] eIF4E:4E-BP [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:72623] Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function
modified[InstanceEdit:110066] Joshi-Tope, G, 2004-01-26 13:16:45
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRelease of eIF4E from the inactive eIF4E:4E-BP complex
output[EntityWithAccessionedSequence:72578] EIF4E [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:72580] EIF4EBP1 [cytosol] [Homo sapiens]
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359040] R-HSA-72622.3
summation[Summation:72630] eIF4E gets released from the inactive eIF4E:4EBP complex. ...
(hasEvent)[Pathway:72662] Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S [Homo sapiens]
(precedingEvent)[Reaction:72631] Formation of the cap-binding eIF4F complex [Homo sapiens]
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No pathways have been reviewed or authored by Release of eIF4E from the inactive eIF4E:4E-BP complex (72622)