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Details on Person UniProt:P62424 RPL7A

Class:Id	ReferenceGeneProduct:72487
_chainChangeLog	initiator methionine:1 added on Fri February 6 2015;chain:2-266 added on Fri February 6 2015
_displayName	UniProt:P62424 RPL7A
_timestamp	2024-11-03 19:43:10
chain	chain:1-266
checksum	54EF43F221D9F704
comment	FUNCTION Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:32669547).SUBUNIT Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). Interacts with CRY1 (By similarity). Interacts with DICER1, AGO2, TARBP2, MOV10 and EIF6; they form a large RNA-induced silencing complex (RISC) (PubMed:17507929).INTERACTION Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene.SIMILARITY Belongs to the eukaryotic ribosomal protein eL8 family.
description	recommendedName: fullName evidence="5"Large ribosomal subunit protein eL8 alternativeName: 60S ribosomal protein L7a alternativeName: PLA-X polypeptide alternativeName: Surfeit locus protein 3
geneName	RPL7A SURF-3 SURF3
identifier	P62424
isSequenceChanged	FALSE
keyword	3D-structure Acetylation Chromosomal rearrangement Cytoplasm Isopeptide bond Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
modified	[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09 [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:2587579] Weiser, JD [InstanceEdit:4341137] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:8987656] Weiser, JD [InstanceEdit:9027688] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9730071] Weiser, JD [InstanceEdit:9796772] Weiser, Joel [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
name	RPL7A
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:8997405] ENSEMBL:ENSG00000148303 RPL7A [Homo sapiens]
secondaryIdentifier	RL7A_HUMAN P11518 Q5T8U4
sequenceLength	266
species	[Species:48887] Homo sapiens
(referenceEntity)	[EntityWithAccessionedSequence:72488] RPL7A [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:P62424 RPL7A (72487)