Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P46778 RPL21
| Class:Id | ReferenceGeneProduct:72425 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-160 added on Fri February 6 2015;initiator methionine:1 for 72425 removed on Fri Nov 03 2023;initiator methionine: for 72425 added on Fri Nov 03 2023;initiator methionine: for 72425 removed on Fri Aug 15 2025;initiator methionine:1 for 72425 added on Fri Aug 15 2025 |
| _displayName | UniProt:P46778 RPL21 |
| _timestamp | 2025-08-15 21:56:25 |
| chain | initiator methionine:1 chain:2-160 |
| checksum | C51D0B5E8EB9D69E |
| comment | FUNCTION Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688).SUBUNIT Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688).SUBCELLULAR LOCATION Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the eukaryotic ribosomal protein eL21 family. |
| description | recommendedName: fullName evidence="8"Large ribosomal subunit protein eL21 alternativeName: 60S ribosomal protein L21 |
| geneName | RPL21 |
| identifier | P46778 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cytoplasm Direct protein sequencing Disease variant Endoplasmic reticulum Hypotrichosis Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | RPL21 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999728] ENSEMBL:ENSG00000122026 RPL21 [Homo sapiens] |
| secondaryIdentifier | RL21_HUMAN Q16699 |
| sequenceLength | 160 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:72426] RPL21 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P46778 RPL21 (72425)
