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Details on Person UniProt:Q07020 RPL18
| Class:Id | ReferenceGeneProduct:72419 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-188 added on Fri February 6 2015;initiator methionine:1 for 72419 removed on Fri Nov 03 2023;initiator methionine: for 72419 added on Fri Nov 03 2023;initiator methionine: for 72419 removed on Fri Aug 15 2025;initiator methionine:1 for 72419 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q07020 RPL18 |
| _timestamp | 2025-08-15 21:02:55 |
| chain | initiator methionine:1 chain:2-188 |
| checksum | C4E416E7A5329B7C |
| comment | FUNCTION Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547).SUBUNIT Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547).INTERACTION Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).ALTERNATIVE PRODUCTS The disease may be caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the eukaryotic ribosomal protein eL18 family. |
| description | recommendedName: fullName evidence="9"Large ribosomal subunit protein eL18 alternativeName: 60S ribosomal protein L18 |
| geneName | RPL18 |
| identifier | Q07020 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Cytoplasm Diamond-Blackfan anemia Direct protein sequencing Disease variant Endoplasmic reticulum Isopeptide bond Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | RPL18 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996838] ENSEMBL:ENSG00000063177 RPL18 [Homo sapiens] |
| secondaryIdentifier | RL18_HUMAN F8VWC5 Q8WTZ6 |
| sequenceLength | 188 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8970719] UniProt:Q07020-1 RPL18 [Homo sapiens] [ReferenceIsoform:8970720] UniProt:Q07020-2 RPL18 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:72420] RPL18 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q07020 RPL18 (72419)
