Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person UniProt:P46782 RPS5

Class:IdReferenceGeneProduct:72378
_chainChangeLoginitiator methionine:1 added on Fri February 6 2015;chain:1-204 added on Fri February 6 2015;chain:2-204 added on Fri February 6 2015;initiator methionine:1 for 72378 removed on Fri Nov 03 2023;initiator methionine: for 72378 added on Fri Nov 03 2023;initiator methionine: for 72378 removed on Fri Aug 15 2025;initiator methionine:1 for 72378 added on Fri Aug 15 2025
_displayNameUniProt:P46782 RPS5
_timestamp2025-08-15 21:26:10
chainchain:1-204
initiator methionine:1
chain:2-204
checksumDFE2FD5AAFCFD894
commentFUNCTION Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the small ribosomal subunit. Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797).INTERACTION Belongs to the universal ribosomal protein uS7 family.
descriptionrecommendedName: fullName evidence="5"Small ribosomal subunit protein uS7 alternativeName: 40S ribosomal protein S5 component recommendedName: Small ribosomal subunit protein uS7, N-terminally processed alternativeName: 40S ribosomal protein S5, N-terminally processed /component
geneNameRPS5
identifierP46782
isSequenceChangedFALSE
keyword3D-structure
Acetylation
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Ribonucleoprotein
Ribosomal protein
Ubl conjugation
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9841277] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
nameRPS5
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8961047] ENSEMBL:ENSG00000083845 RPS5 [Homo sapiens]
secondaryIdentifierRS5_HUMAN
B2R4T2
Q96BN0
sequenceLength204
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:72379] RPS5 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:6791188] RPS5 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:8961287] RPS5 [extracellular region] [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by UniProt:P46782 RPS5 (72378)