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Details on Person UniProt:P62861 FAU
| Class:Id | ReferenceGeneProduct:72370 |
|---|---|
| _chainChangeLog | chain:1-59 added on Sat February 7 2015;chain:1-59 for 72370 removed on Wed May 4 2022;chain:1-133 for 72370 added on Wed May 4 2022;chain:1-74 for 72370 added on Wed May 4 2022;chain:75-133 for 72370 added on Wed May 4 2022 |
| _displayName | UniProt:P62861 FAU |
| _timestamp | 2024-11-03 20:16:27 |
| chain | chain:1-133 chain:1-74 chain:75-133 |
| checksum | 5D2F81F2A355B559 |
| comment | FUNCTION May have pro-apoptotic activity.FUNCTION Component of the 40S subunit of the ribosome. Contributes to the assembly and function of 40S ribosomal subunits.SUBUNIT Component of the 40S subunit of the ribosome.INTERACTION FUBI is cleaved from ribosomal protein S30 by the deubiquitinase USP36 before the assembly of ribosomal protein S30 into pre-40S ribosomal particles. FUBI removal from ribosomal protein S30 is a crucial event for the final maturation of pre-40S particles.MISCELLANEOUS FAU encodes a fusion protein consisting of the ubiquitin-like protein FUBI at the N terminus and ribosomal protein S30 at the C terminus.MISCELLANEOUS Lacks the typical lysine residues that participate in Ub's polyubiquitination. However contains a C-terminal di-glycine signature after its proteolytic separation from ribosomal protein S30 and could theoretically be conjugated onto target proteins.SIMILARITY In the N-terminal section; belongs to the ubiquitin family.SIMILARITY In the C-terminal section; belongs to the eukaryotic ribosomal protein eS30 family. |
| description | recommendedName: fullName evidence="10"Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein alternativeName: fullName evidence="12"FAU ubiquitin like and ribosomal protein S30 fusion component recommendedName: Ubiquitin-like protein FUBI /component component recommendedName: fullName evidence="9"Small ribosomal subunit protein eS30 alternativeName: 40S ribosomal protein S30 /component |
| geneName | FAU |
| identifier | P62861 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cytoplasm Direct protein sequencing Nucleus Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | FAU |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8988639] ENSEMBL:ENSG00000149806 FAU [Homo sapiens] |
| secondaryIdentifier | RS30_HUMAN P35544 Q05472 Q95261 Q9H5V4 |
| sequenceLength | 133 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:72371] FAU [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6798717] FAU [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P62861 FAU (72370)
