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Details on Person UniProt:P62857 RPS28
| Class:Id | ReferenceGeneProduct:72364 |
|---|---|
| _chainChangeLog | chain:1-69 added on Fri February 6 2015 |
| _displayName | UniProt:P62857 RPS28 |
| _timestamp | 2024-11-03 19:48:22 |
| chain | chain:1-69 |
| checksum | 49902FE9376EB74F |
| comment | FUNCTION Component of the small ribosomal subunit (PubMed:23636399, PubMed:25901680, PubMed:25957688). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:25957688). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the 40S small ribosomal subunit (PubMed:23636399, PubMed:25901680, PubMed:25957688). Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797).INTERACTION Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the eukaryotic ribosomal protein eS28 family. |
| description | recommendedName: fullName evidence="8"Small ribosomal subunit protein eS28 alternativeName: 40S ribosomal protein S28 |
| geneName | RPS28 |
| identifier | P62857 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Cytoplasm Diamond-Blackfan anemia Direct protein sequencing Endoplasmic reticulum Nucleus Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | RPS28 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9000288] ENSEMBL:ENSG00000233927 RPS28 [Homo sapiens] |
| secondaryIdentifier | RS28_HUMAN P25112 |
| sequenceLength | 69 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:72365] RPS28 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6791202] RPS28 [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P62857 RPS28 (72364)
