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Details on Person UniProt:P62847 RPS24
| Class:Id | ReferenceGeneProduct:72354 |
|---|---|
| _chainChangeLog | chain:1-133 added on Fri February 6 2015 |
| _displayName | UniProt:P62847 RPS24 |
| _timestamp | 2026-02-20 22:48:41 |
| chain | chain:1-133 |
| checksum | CE9065C0764D60A6 |
| comment | FUNCTION Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Required for processing of pre-rRNA and maturation of 40S ribosomal subunits (PubMed:18230666). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the small ribosomal subunit (PubMed:23636399). Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797).INTERACTION Mature tissues, such as adult brain, skeletal muscle, heart, and kidney, express low levels, whereas tissues and organs with significant populations of proliferating cells, such as fetal brain, placenta, bone marrow, and various glandular organs, contain significantly higher levels.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the eukaryotic ribosomal protein eS24 family. |
| description | recommendedName: fullName evidence="10"Small ribosomal subunit protein eS24 alternativeName: 40S ribosomal protein S24 |
| geneName | RPS24 |
| identifier | P62847 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing Cytoplasm Diamond-Blackfan anemia Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | RPS24 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999746] ENSEMBL:ENSG00000138326 RPS24 [Homo sapiens] |
| secondaryIdentifier | RS24_HUMAN E7EPK6 P16632 Q5T0P7 Q5T0P8 Q7Z3D1 |
| sequenceLength | 133 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:153325] UniProt:P62847-2 RPS24 [Homo sapiens] [ReferenceIsoform:404625] UniProt:P62847-1 RPS24 [Homo sapiens] [ReferenceIsoform:8965809] UniProt:P62847-3 RPS24 [Homo sapiens] [ReferenceIsoform:8965810] UniProt:P62847-4 RPS24 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:72355] RPS24 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6791186] RPS24 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P62847 RPS24 (72354)
