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Details on Person UniProt:P62277 RPS13
| Class:Id | ReferenceGeneProduct:72330 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-151 added on Fri February 6 2015;initiator methionine:1 for 72330 removed on Fri Nov 03 2023;initiator methionine: for 72330 added on Fri Nov 03 2023;initiator methionine: for 72330 removed on Fri Aug 15 2025;initiator methionine:1 for 72330 added on Fri Aug 15 2025 |
| _displayName | UniProt:P62277 RPS13 |
| _timestamp | 2025-08-15 21:03:03 |
| chain | initiator methionine:1 chain:2-151 |
| checksum | 23F94D38F87B8D53 |
| comment | FUNCTION Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the small ribosomal subunit. Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797).INTERACTION Ubiquitinated at Lys-27 by RNF14 and RNF25 in response to ribosome collisions (ribosome stalling).SIMILARITY Belongs to the universal ribosomal protein uS15 family. |
| description | recommendedName: fullName evidence="6"Small ribosomal subunit protein uS15 alternativeName: 40S ribosomal protein S13 |
| geneName | RPS13 |
| identifier | P62277 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | RPS13 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9003791] ENSEMBL:ENSG00000110700 RPS13 [Homo sapiens] |
| secondaryIdentifier | RS13_HUMAN B2R549 P19116 Q02546 Q29200 Q498Y0 |
| sequenceLength | 151 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:72331] RPS13 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6791198] RPS13 [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P62277 RPS13 (72330)
