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Details on Person UniProt:P62280 RPS11
| Class:Id | ReferenceGeneProduct:72326 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-158 added on Sat February 7 2015;initiator methionine:1 for 72326 removed on Fri Nov 03 2023;initiator methionine: for 72326 added on Fri Nov 03 2023;initiator methionine: for 72326 removed on Fri Aug 15 2025;initiator methionine:1 for 72326 added on Fri Aug 15 2025 |
| _displayName | UniProt:P62280 RPS11 |
| _timestamp | 2025-08-15 22:11:33 |
| chain | initiator methionine:1 chain:2-158 |
| checksum | 9FB75DC1D99614B0 |
| comment | FUNCTION Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the small ribosomal subunit. Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797).INTERACTION Citrullinated by PADI4.SIMILARITY Belongs to the universal ribosomal protein uS17 family. |
| description | recommendedName: fullName evidence="6"Small ribosomal subunit protein uS17 alternativeName: 40S ribosomal protein S11 |
| geneName | RPS11 |
| identifier | P62280 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Citrullination Cytoplasm Direct protein sequencing Lipoprotein Methylation Nucleus Palmitate Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | RPS11 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9003790] ENSEMBL:ENSG00000142534 RPS11 [Homo sapiens] |
| secondaryIdentifier | RS11_HUMAN B2R4F5 P04643 Q498Y6 Q6IRY0 |
| sequenceLength | 158 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:72327] RPS11 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6791212] RPS11 [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P62280 RPS11 (72326)
