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Details on Person UniProt:Q9Y2P8 RCL1
| Class:Id | ReferenceGeneProduct:72284 |
|---|---|
| _chainChangeLog | chain:1-373 added on Sat February 7 2015 |
| _displayName | UniProt:Q9Y2P8 RCL1 |
| _timestamp | 2026-02-20 21:33:46 |
| chain | chain:1-373 |
| checksum | 533FAE8420AF93CB |
| comment | FUNCTION As part of the small subunit (SSU) processome, it plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity). Activates BMS1 by promoting GDP/GTP exchange (By similarity). Does not have cyclase activity (By similarity).SUBUNIT Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797). Interacts with BMS1 (PubMed:27474224).SUBCELLULAR LOCATION Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. |
| description | recommendedName: RNA 3'-terminal phosphate cyclase-like protein |
| geneName | RCL1 RNAC RPC2 RPCL1 RTC2 HSPC338 |
| identifier | Q9Y2P8 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Nucleus Proteomics identification Reference proteome Ribosome biogenesis |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9948485] Weiser, Joel, 2025-05-21 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | RCL1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997393] ENSEMBL:ENSG00000120158 RCL1 [Homo sapiens] |
| secondaryIdentifier | RCL1_HUMAN D3DRI2 Q5VYW9 Q5VZU1 Q9H9D0 Q9NY00 Q9P044 |
| sequenceLength | 373 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8978011] UniProt:Q9Y2P8-1 RCL1 [Homo sapiens] [ReferenceIsoform:8978012] UniProt:Q9Y2P8-2 RCL1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:6790711] RCL1 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9Y2P8 RCL1 (72284)
