Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:O15116 LSM1
| Class:Id | ReferenceGeneProduct:72274 |
|---|---|
| _chainChangeLog | chain:1-133 added on Fri February 6 2015 |
| _displayName | UniProt:O15116 LSM1 |
| _timestamp | 2026-02-20 21:50:48 |
| chain | chain:1-133 |
| checksum | FF798CDA9447037A |
| comment | FUNCTION Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (PubMed:18172165). Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).SUBUNIT Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase (PubMed:18172165). LSm subunits form a heteromer with a donut shape (By similarity).INTERACTION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the snRNP Sm proteins family. |
| description | recommendedName: U6 snRNA-associated Sm-like protein LSm1 alternativeName: Cancer-associated Sm-like alternativeName: Small nuclear ribonuclear CaSm |
| geneName | LSM1 CASM |
| identifier | O15116 |
| isSequenceChanged | FALSE |
| keyword | Cytoplasm mRNA processing mRNA splicing Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein RNA-binding |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | LSM1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8989046] ENSEMBL:ENSG00000175324 LSM1 [Homo sapiens] |
| secondaryIdentifier | LSM1_HUMAN B2R5E6 |
| sequenceLength | 133 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:429976] LSM1 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O15116 LSM1 (72274)
