Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person UniProt:Q13242 SRSF9

Class:IdReferenceGeneProduct:72036
_chainChangeLogchain:1-221 added on Fri February 6 2015
_displayNameUniProt:Q13242 SRSF9
_timestamp2024-11-03 20:21:38
chainchain:1-221
checksum1EE7BD8601CD80C0
commentFUNCTION Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.SUBUNIT Interacts with KHDRBS3 (By similarity). Interacts with HABP4 (PubMed:19523114). Interacts with NOL3/ARC/NOP30 (PubMed:10196175). Interacts with NSEP1/YB-1/YB1 (PubMed:12604611). Interacts with SAFB/SAFB1 (PubMed:11694584, PubMed:9671816). Interacts with SRSF6/SFRS6 (PubMed:15695522). Interacts with TRA2B/SFRS10 (PubMed:11875052, PubMed:15695522). Interacts with C1QBP (PubMed:10022843). May also interact with DUSP11/PIR1 (PubMed:11694584).INTERACTION Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.TISSUE SPECIFICITY Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.PTM Extensively phosphorylated on serine residues in the RS domain.SIMILARITY Belongs to the splicing factor SR family.
descriptionrecommendedName: Serine/arginine-rich splicing factor 9 alternativeName: Pre-mRNA-splicing factor SRp30C alternativeName: Splicing factor, arginine/serine-rich 9
geneNameSRSF9
SFRS9
SRP30C
identifierQ13242
isSequenceChangedFALSE
keywordIsopeptide bond
mRNA processing
mRNA splicing
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Repressor
RNA-binding
Ubl conjugation
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameSRSF9
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8995150] ENSEMBL:ENSG00000111786 SRSF9 [Homo sapiens]
secondaryIdentifierSRSF9_HUMAN
Q52LD1
sequenceLength221
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:72037] SRSF9 [nucleoplasm] [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by UniProt:Q13242 SRSF9 (72036)
Follow Reactome