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Details on Person UniProt:Q08170 SRSF4
| Class:Id | ReferenceGeneProduct:72023 |
|---|---|
| _chainChangeLog | chain:1-494 added on Sat February 7 2015 |
| _displayName | UniProt:Q08170 SRSF4 |
| _timestamp | 2024-11-03 19:43:37 |
| chain | chain:1-494 |
| checksum | 5BBAB917C218C20A |
| comment | FUNCTION Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.SUBUNIT Found in a pre-mRNA splicing complex with SRSF4/SFRS4, SRSF5/SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN.INTERACTION Extensively phosphorylated on serine residues in the RS domain.SIMILARITY Belongs to the splicing factor SR family. |
| description | recommendedName: Serine/arginine-rich splicing factor 4 alternativeName: Pre-mRNA-splicing factor SRP75 alternativeName: SRP001LB alternativeName: Splicing factor, arginine/serine-rich 4 |
| geneName | SRSF4 SFRS4 SRP75 |
| identifier | Q08170 |
| isSequenceChanged | FALSE |
| keyword | Direct protein sequencing mRNA processing mRNA splicing Nucleus Phosphoprotein Proteomics identification Reference proteome Repeat Repressor RNA-binding |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | SRSF4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997457] ENSEMBL:ENSG00000116350 SRSF4 [Homo sapiens] |
| secondaryIdentifier | SRSF4_HUMAN Q5VXP1 Q9BUA4 Q9UEB5 |
| sequenceLength | 494 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:72024] SRSF4 [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q08170 SRSF4 (72023)
