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Details on Person UniProt:Q9P2I0 CPSF2
| Class:Id | ReferenceGeneProduct:71990 |
|---|---|
| _chainChangeLog | chain:1-782 added on Fri February 6 2015 |
| _displayName | UniProt:Q9P2I0 CPSF2 |
| _timestamp | 2024-11-03 20:18:31 |
| chain | chain:1-782 |
| checksum | F67B4813B9883CE8 |
| comment | FUNCTION Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.SUBUNIT Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Interacts with CPSF3, CSTF2 and SYMPK. Interacts with ZC3H3 (By similarity).INTERACTION Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily. |
| description | recommendedName: Cleavage and polyadenylation specificity factor subunit 2 alternativeName: Cleavage and polyadenylation specificity factor 100 kDa subunit shortName: CPSF 100 kDa subunit |
| geneName | CPSF2 CPSF100 KIAA1367 |
| identifier | Q9P2I0 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure mRNA processing Nucleus Phosphoprotein Proteomics identification Reference proteome RNA-binding |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CPSF2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999408] ENSEMBL:ENSG00000165934 CPSF2 [Homo sapiens] |
| secondaryIdentifier | CPSF2_HUMAN B3KME1 Q6NSJ1 Q9H3W7 |
| sequenceLength | 782 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:71991] CPSF2 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9P2I0 CPSF2 (71990)
