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Details on Person PGK complexes dephosphorylate 1,3BPG
Class:Id Reaction:71850
_displayName PGK complexes dephosphorylate 1,3BPG
_doRelease TRUE
_timestamp 2025-01-01 11:07:21
catalystActivity [CatalystActivity:70485] phosphoglycerate kinase activity of PGK complexes [cytosol]
catalystActivityReference [CatalystActivityReference:9643186] phosphoglycerate kinase activity of PGK complexes [cytosol] Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme
compartment [Compartment:70101] cytosol
crossReference [DatabaseIdentifier:9933516] RHEA:14803
input [SimpleEntity:29800] 1,3BPG [cytosol] [SimpleEntity:29370] ADP [cytosol]
literatureReference [LiteratureReference:6808365] Characterization of phosphoglycerate kinase from human spermatozoa [LiteratureReference:141559] Complete amino acid sequence of human phosphoglycerate kinase. Isolation and amino acid sequence of tryptic peptides. [LiteratureReference:141486] Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence. [LiteratureReference:6807621] Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene [LiteratureReference:450670] Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme
modified [InstanceEdit:74479] D'Eustachio, P, 2003-07-22 16:21:00 [InstanceEdit:141589] D'Eustachio, P, 2004-09-21 16:29:03 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:198534] D'Eustachio, P, 2007-06-22 15:53:40 [InstanceEdit:450636] D'Eustachio, P, 2009-12-16 [InstanceEdit:450684] D'Eustachio, P, 2009-12-16 [InstanceEdit:6808363] D'Eustachio, Peter, 2015-11-04 [InstanceEdit:6809180] D'Eustachio, Peter, 2015-11-09 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9655714] D'Eustachio, Peter, 2019-07-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
name PGK complexes dephosphorylate 1,3BPG 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP 1,3-Bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
output [SimpleEntity:29728] 3PG [cytosol] [SimpleEntity:113592] ATP [cytosol]
precedingEvent
releaseDate 2004-07-06
reverseReaction
reviewed [InstanceEdit:6809181] Jassal, Bijay, 2015-11-09
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:450685] D'Eustachio, P, 2009-12-16 [InstanceEdit:6809179] D'Eustachio, Peter, 2015-11-09
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360622] R-HSA-71850.7
summation [Summation:71784] Cytosolic phosphoglycerate kinase (PGK) catalyzes the reacti...
(hasEvent) [Pathway:70171] Glycolysis [Homo sapiens]
(precedingEvent) [Reaction:71654] PGAM dimers isomerise 3PG to 2PG [Homo sapiens]
(replacementInstances) [_Deleted:450680] Deletion of instance: 70105
(reverseReaction) [Reaction:70486] PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG [Homo sapiens]
(updatedInstance) [_UpdateTracker:9784022] Update Tracker - [Reaction:71850] 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP - v55:[addLiteratureReference, modifyText] [_UpdateTracker:9791238] Update Tracker - [Reaction:71850] 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP - v32:[addLiteratureReference, modifyText] [_UpdateTracker:9792219] Update Tracker - [Reaction:71850] 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP - v22:[modifyText]
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