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Details on Person PGAM dimers isomerise 3PG to 2PG

Class:Id	Reaction:71654
_displayName	PGAM dimers isomerise 3PG to 2PG
_doRelease	TRUE
_timestamp	2025-01-01 11:07:01
catalystActivity	[CatalystActivity:71444] phosphoglycerate mutase activity of PGAM dimers [cytosol]
catalystActivityReference	[CatalystActivityReference:9643632] phosphoglycerate mutase activity of PGAM dimers [cytosol] Phosphoglycerate mutase isozyme marker for tissue differentiation in man
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:9933533] RHEA:15903
input	[SimpleEntity:29728] 3PG [cytosol]
literatureReference	[LiteratureReference:141498] Sequence of the human erythrocyte phosphoglycerate mutase by microsequencer and mass spectrometry [LiteratureReference:450653] Phosphoglycerate mutase isozyme marker for tissue differentiation in man [LiteratureReference:198474] Phosphoglycerate mutase BB isoenzyme deficiency in a patient with non-spherocytic anemia: familial and metabolic studies [LiteratureReference:198514] The molecular genetic basis of muscle phosphoglycerate mutase (PGAM) deficiency
modified	[InstanceEdit:141587] D'Eustachio, P, 2004-09-21 16:28:50 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:198480] D'Eustachio, P, 2007-06-22 14:17:01 [InstanceEdit:350357] D'Eustachio, P, 2008-05-19 12:45:16 [InstanceEdit:450636] D'Eustachio, P, 2009-12-16 [InstanceEdit:450684] D'Eustachio, P, 2009-12-16 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9793234] D'Eustachio, Peter, 2022-06-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
name	PGAM dimers isomerise 3PG to 2PG 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate
output	[SimpleEntity:30485] 2PG [cytosol]
precedingEvent	[Reaction:71850] PGK complexes dephosphorylate 1,3BPG [Homo sapiens] [Reaction:70449] GADPH tetramer dehydrogenates GA3P [Homo sapiens] [Reaction:8955760] PGM2L1:Mg2+ phosphorylates G6P to G1,6BP [Homo sapiens] [Reaction:70420] HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P [Homo sapiens] [Reaction:70475] GPI dimer isomerizes Fru(6)P to G6P [Homo sapiens]
releaseDate	2004-07-06
reverseReaction	[Reaction:71445] PGAM dimers isomerise 2PG to 3PG [Homo sapiens] [Reaction:71654] PGAM dimers isomerise 3PG to 2PG [Homo sapiens]
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:450685] D'Eustachio, P, 2009-12-16
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358874] R-HSA-71654.6
summation	[Summation:71655] Cytosolic phosphoglycerate mutase catalyzes the reversible i...
(hasEvent)	[Pathway:70171] Glycolysis [Homo sapiens]
(precedingEvent)	[Reaction:71660] Enolase dimers dehydrates 2PG [Homo sapiens]
(reverseReaction)	[Reaction:71445] PGAM dimers isomerise 2PG to 3PG [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791144] Update Tracker - [Reaction:71654] 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate - v32:[addLiteratureReference, modifyText] [_UpdateTracker:9792328] Update Tracker - [Reaction:71654] 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate - v22:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by PGAM dimers isomerise 3PG to 2PG (71654)