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Details on Person glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]

Class:Id	Reaction:71515
_displayName	glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
_doRelease	TRUE
_timestamp	2024-12-11 20:54:10
catalystActivity	[CatalystActivity:71514] glycogen phosphorylase activity of active PYGM and PYGB dimers [cytosol]
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:9931451] RHEA:41733
inferredFrom	[Reaction:71590] glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] [Homo sapiens]
input	[Complex:453239] glycogen-glycogenin-1 dimer [cytosol] [Homo sapiens] [SimpleEntity:29372] Pi [cytosol]
literatureReference	[LiteratureReference:453326] Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core [LiteratureReference:453361] The family of glycogen phosphorylases: structure and function
modified	[InstanceEdit:73440] D'Eustachio, P, 2003-06-16 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:453123] D'Eustachio, P, 2010-01-18 [InstanceEdit:453352] D'Eustachio, P, 2010-01-21 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9931474] D'Eustachio, Peter, 2024-12-11
name	glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] ((1->4)-alpha-D-glucosyl)(n) + phosphate => ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
output	[Complex:453345] limit dextrin-glycogenin-1 dimer [cytosol] [Homo sapiens] [SimpleEntity:29548] G1P [cytosol]
precedingEvent	[Reaction:453337] glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP [Homo sapiens] [Reaction:453346] PYGB b dimer:AMP complex => PGYB dimer, b form + 2 AMP [Homo sapiens] [Reaction:71541] glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP [Homo sapiens] [Reaction:453338] PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP [Homo sapiens] [Reaction:453356] PYGB dimer, b form + 2 AMP => PYGB b dimer:AMP complex [Homo sapiens] [Reaction:453342] PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex [Homo sapiens] [Reaction:453338] PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:453329] D'Eustachio, P, 2010-01-21
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358463] R-HSA-71515.4
summation	[Summation:178819] The PYGM and PYGB forms of glycogen phosphorylase catalyze t...
(hasEvent)	[Pathway:70221] Glycogen breakdown (glycogenolysis) [Homo sapiens]
(precedingEvent)	[Reaction:71552] limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin [Homo sapiens] [Reaction:9638125] PGM1:Mg2+ isomerises G1P to G6P [Homo sapiens] [NegativePrecedingEvent:9931453] Abundant Molecules: glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
(replacementInstances)	[_Deleted:453368] Deletion of instance: 71543 [_Deleted:453371] Deletion of instance: 70182
(updatedInstance)	[_UpdateTracker:9790855] Update Tracker - [Reaction:71515] glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] - v32:[add_removeInput, add_removeLiteratureReference, add_removeOutput, modifyText]
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No pathways have been reviewed or authored by glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] (71515)