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Details on Person Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase

Class:IdLiteratureReference:71418
_displayNameStructure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase
_timestamp2003-10-30 07:42:48
author[Person:70551] Horwich, AL
[Person:71001] Fenton, WA
[Person:71419] Williams, KR
[Person:71420] Kalousek, F
[Person:71421] Kraus, JP
[Person:71422] Doolittle, RF
[Person:71423] Konigsberg, W
[Person:71424] Rosenberg, LE
journalScience
pages1068-74
pubMedIdentifier6372096
titleStructure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.
volume224
year1984
(literatureReference)[Reaction:70560] carbamoyl phosphate + ornithine => citrulline + orthophosphate [Homo sapiens]
[BlackBoxEvent:9956502] OTC precursor is targeted to the mitochondrial matrix and processed [Homo sapiens]
[FailedReaction:9956513] Leader sequence variants of OTC aren't targeted to the mitochondria [Homo sapiens]
[Pathway:9956522] OTC variants cause OTC deficiency [Homo sapiens]
[Pathway:9956551] OTC leader sequence variants cause OTC deficiency [Homo sapiens]
[CatalystActivityReference:9643158] ornithine carbamoyltransferase activity of OTC trimer [mitochondrial matrix] Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase
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