Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Mitochondrial malate dehydrogenase (MDH2) dimer catalyzes th...
| Class:Id | Summation:71413 |
|---|---|
| _displayName | Mitochondrial malate dehydrogenase (MDH2) dimer catalyzes th... |
| _timestamp | 2023-11-23 10:33:38 |
| modified | [InstanceEdit:141448] Matthews, L, 2004-09-20 15:43:00 [InstanceEdit:198405] D'Eustachio, P, 2007-06-18 16:46:57 [InstanceEdit:198480] D'Eustachio, P, 2007-06-22 14:17:01 [InstanceEdit:451044] D'Eustachio, P, 2009-12-26 [InstanceEdit:9815858] D'Eustachio, Peter, 2022-08-29 [InstanceEdit:9854222] Stephan, Ralf, 2023-11-23 |
| text | Mitochondrial malate dehydrogenase (MDH2) dimer catalyzes the reversible reaction of malate and NAD+ to form oxaloacetate (OA) and NADH + H+ (Luo et al. 2006; Eo et al., 2022). This reaction is highly endergonic but is pulled in the direction annotated here when the TCA cycle is operating. The active enzyme is a palmitoylated homodimer (Sanchez et al. 1998; Pei et al., 2022). Mutations in MDH2 can cause infantile epileptic encephalopathy (DEE51, MIM:617339; see Priestley et al., 2022). |
| (summation) | [Reaction:70979] MDH2 dimer dehydrogenates MAL [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Mitochondrial malate dehydrogenase (MDH2) dimer catalyzes th... (71413)
